Human Health Exposure Analysis Resource

Last uploaded: July 19, 2024
Preferred Name

monoblast
Synonyms

colony forming unit monocyte

monocyte stem cell

colony forming unit macrophage

CFU-M

Definitions

A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.

ID

http://purl.obolibrary.org/obo/CL_0000040

comment

Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.

alternative label

colony forming unit monocyte

monocyte stem cell

colony forming unit macrophage

CFU-M

database_cross_reference

CALOHA:TS-1195

ZFA:0009017

FMA:83553

definition

A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus.

Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.

develops_from

http://purl.obolibrary.org/obo/CL_0002009

has part

http://purl.obolibrary.org/obo/GO_0000791

http://purl.obolibrary.org/obo/GO_0005730

http://purl.obolibrary.org/obo/CL_0017503

http://purl.obolibrary.org/obo/PR_000001012

has plasma membrane part

http://purl.obolibrary.org/obo/PR_000001012

has_related_synonym

colony forming unit monocyte

monocyte stem cell

colony forming unit macrophage

CFU-M

label

monoblast

note

A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus.

Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.

overlaps

http://purl.obolibrary.org/obo/GO_0000791

http://purl.obolibrary.org/obo/GO_0005730

http://purl.obolibrary.org/obo/CL_0017503

http://purl.obolibrary.org/obo/PR_000001012

preferred label

monoblast

prefixIRI

CL:0000040

prefLabel

monoblast

treeView

http://purl.obolibrary.org/obo/CL_0002009

subClassOf

http://purl.obolibrary.org/obo/PR_000050567

http://purl.obolibrary.org/obo/CL_0000763

http://purl.obolibrary.org/obo/CL_0002194

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CL_0000040 CL SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 UBERON SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 CLO SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 CCONT SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 CHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 NGBO SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 OBI_BCGO SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 EFO SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 PCL SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 EFO SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 KTAO SAME_URI
http://purl.obolibrary.org/obo/CL_0000040 OBA SAME_URI
http://purl.bioontology.org/ontology/SNMI/T-C1710 SNMI LOOM
http://www.co-ode.org/ontologies/galen#Monoblast GALEN LOOM
http://purl.org/obo/owlapi/fma#FMA_83553 BIOMODELS LOOM
http://purl.org/sig/ont/fma/fma83553 FMA LOOM
http://purl.obolibrary.org/obo/XAO_0006034 XAO LOOM
http://purl.bioontology.org/ontology/RCD/X80VL RCD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/53945006 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/TAO_0009017 TAO LOOM
http://purl.obolibrary.org/obo/ZFA_0009017 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0009017 ZP LOOM
http://purl.org/obo/owl/CL#CL_0000040 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CL_0000040 CL LOOM
http://purl.obolibrary.org/obo/CL_0000040 UBERON LOOM
http://purl.obolibrary.org/obo/CL_0000040 CLO LOOM
http://purl.obolibrary.org/obo/CL_0000040 CCONT LOOM
http://purl.obolibrary.org/obo/CL_0000040 CHEAR LOOM
http://purl.obolibrary.org/obo/CL_0000040 NGBO LOOM
http://purl.obolibrary.org/obo/CL_0000040 OBI_BCGO LOOM
http://purl.obolibrary.org/obo/CL_0000040 EFO LOOM
http://purl.obolibrary.org/obo/CL_0000040 PCL LOOM
http://purl.obolibrary.org/obo/CL_0000040 NIFDYS LOOM
http://purl.obolibrary.org/obo/CL_0000040 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CL_0000040 EFO LOOM
http://purl.obolibrary.org/obo/CL_0000040 UPHENO LOOM
http://purl.obolibrary.org/obo/CL_0000040 NIFSTD LOOM
http://purl.obolibrary.org/obo/CL_0000040 KTAO LOOM
http://purl.obolibrary.org/obo/CL_0000040 OBA LOOM
http://purl.obolibrary.org/obo/NCIT_C13014 BERO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13014 NCIT LOOM