Preferred Name |
dutasteride |
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Synonyms |
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Definitions |
An aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_521033 |
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ATC Code |
G04CB02 |
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ChEBI ID | ||
definition |
An aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland. |
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has database cross reference | ||
label |
dutasteride |
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MeSH Descriptor ID | ||
NCI Thesaurus ID | ||
prefixIRI |
CHEBI:521033 |
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prefLabel |
dutasteride |
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RxNorm ID | ||
SNOMED CT Identifier | ||
subClassOf |
http://purl.obolibrary.org/obo/CHEBI_35726 |