Preferred Name | zidovudine | |
Synonyms |
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Definitions |
A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_10110 |
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ATC Code |
J05AF01 |
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ChEBI ID | ||
definition |
A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. |
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has database cross reference | ||
has synonym |
azidothymidine |
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identifier | ||
is referenced by |
https://books.google.com/books/?id=ymkYAAAAIAAJ |
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label |
zidovudine |
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Library of Congress Subject Headings | ||
medical condition treated | ||
name |
ZDV |
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NCI Thesaurus ID | ||
prefixIRI |
CHEBI:10110 |
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prefLabel |
zidovudine |
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short name |
ZDV |
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SNOMED CT Identifier | ||
subClassOf |