Preferred Name

zidovudine
Synonyms
Definitions

A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines.

ID

http://purl.obolibrary.org/obo/CHEBI_10110

ATC Code

J05AF01

ChEBI ID

http://purl.obolibrary.org/obo/CHEBI_10110

definition

A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.

A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines.

has database cross reference

https://www.wikidata.org/wiki/Q198504

https://en.wikipedia.org/wiki/Zidovudine

has synonym

azidothymidine

identifier

http://purl.obolibrary.org/obo/HIV_5739

is referenced by

https://books.google.com/books/?id=ymkYAAAAIAAJ

https://books.google.com/books/?id=851qoMjA3icC

https://web.archive.org/web/20190102184708/https://www.theaidsinstitute.org/education/aids-101/glossary-hivaids-related-terms

label

zidovudine

Library of Congress Subject Headings

http://id.loc.gov/authorities/subjects/sh89007049

medical condition treated

http://purl.obolibrary.org/obo/GSSO_006944

http://purl.obolibrary.org/obo/GSSO_000521

name

ZDV

NCI Thesaurus ID

http://purl.obolibrary.org/obo/NCIT_C947

prefixIRI

CHEBI:10110

prefLabel

zidovudine

short name

ZDV

SNOMED CT Identifier

http://purl.bioontology.org/ontology/SNOMEDCT/387151007

subClassOf

http://purl.obolibrary.org/obo/CHEBI_22680

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