loading...| Preferred Name |
tRNA |
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| Synonyms |
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| ID |
http://www.bootstrep.eu/ontology/GRO#tRNA |
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| definition |
Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. [SO:0000253, http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00005, ISBN:0198506732] |
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| label |
tRNA |
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| prefixIRI |
GRO:tRNA |
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| prefLabel |
tRNA |
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| reference |
SO:0000253 tRNA |
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| subClassOf |