Gene Regulation Ontology

Last uploaded: January 6, 2016
Preferred Name

RNA interference
Synonyms
ID

http://www.bootstrep.eu/ontology/GRO#RNAInterference

definition

The process by which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. [GO:0016246]

label

RNA interference

prefixIRI

GRO:RNAInterference

prefLabel

RNA interference

reference

GO:0016246 RNA interference

subClassOf

http://www.bootstrep.eu/ontology/GRO#GeneSilencing

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