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Last uploaded:
November 12, 2024
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| Preferred Name | mitogen-activated protein kinase | |
| Synonyms |
kinase-related transforming protein MAPK |
|
| Definitions |
A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY. |
|
| ID |
http://purl.obolibrary.org/obo/PR_000000019 |
|
| definition |
A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY.
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|
| has_exact_synonym |
MAPK
|
|
| has_related_synonym |
kinase-related transforming protein
|
|
| label |
mitogen-activated protein kinase
|
|
| prefixIRI |
PR:000000019
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|
| prefLabel |
mitogen-activated protein kinase
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| subClassOf |
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