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Last uploaded: September 16, 2024
Preferred Name

mitogen-activated protein kinase
Synonyms

kinase-related transforming protein

MAPK

Definitions

A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY.

ID

http://purl.obolibrary.org/obo/PR_000000019

definition

A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY.

has_exact_synonym

MAPK

has_related_synonym

kinase-related transforming protein

label

mitogen-activated protein kinase

prefixIRI

PR:000000019

prefLabel

mitogen-activated protein kinase

subClassOf

http://purl.obolibrary.org/obo/PR_000000001

http://purl.obolibrary.org/obo/CHEBI_36080

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