loading...| Preferred Name | RNA interference | |
| Synonyms |
posttranscriptional gene silencing by siRNA RNAi |
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| Definitions |
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'. |
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| ID |
http://purl.obolibrary.org/obo/GO_0016246 |
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| comment |
Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'. |
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| database_cross_reference |
Wikipedia:RNA_interference |
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| definition |
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. |
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| has_exact_synonym |
posttranscriptional gene silencing by siRNA RNAi |
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| has_obo_namespace |
biological_process |
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| id |
GO:0016246 |
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| label |
RNA interference |
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| notation |
GO:0016246 |
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| prefLabel |
RNA interference |
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| treeView | ||
| subClassOf |