Gene Expression Ontology

Last uploaded: December 16, 2015
Preferred Name

epistasis
Synonyms

epistatic genetic interaction (sensu inequality)

epistatic

Definitions

An effect in which individual perturbations of two different genes result in different mutant phenotypes, and the resulting phenotype of their combination (the double mutant) is equal to that of only one of the perturbations. With respect to any single quantifiable phenotype, this may be expressed as an inequality as - \n\n(a !-eq- wt AND b !-eq- wt AND a !-eq- b) AND (ab -eq- a OR ab -eq- b)\n\nwhere 'a' and 'b' are the observed phenotype values of the individual perturbations, 'ab' is the observed phenotype value of the double perturbation, 'wt' is the wild type phenotype value and 'a !-eq- b' indicates qualitatively or quantitatively different phenotypes.

ID

http://purl.obolibrary.org/obo/MI_0797

altLabel

epistatic genetic interaction (sensu inequality)

epistatic

definition

An effect in which individual perturbations of two different genes result in different mutant phenotypes, and the resulting phenotype of their combination (the double mutant) is equal to that of only one of the perturbations. With respect to any single quantifiable phenotype, this may be expressed as an inequality as - \n\n(a !-eq- wt AND b !-eq- wt AND a !-eq- b) AND (ab -eq- a OR ab -eq- b)\n\nwhere 'a' and 'b' are the observed phenotype values of the individual perturbations, 'ab' is the observed phenotype value of the double perturbation, 'wt' is the wild type phenotype value and 'a !-eq- b' indicates qualitatively or quantitatively different phenotypes.

hasOBONamespace

PSI-MI

id

MI:0797

inSubset

http://purl.obolibrary.org/obo/obo#PSI-MI_slim

notation

MI:0797

prefLabel

epistasis

subClassOf

http://purl.obolibrary.org/obo/MI_0208

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