Preferred Name | RNA interference | |
Synonyms |
posttranscriptional gene silencing by siRNA RNAi |
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Definitions |
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. |
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ID |
http://purl.obolibrary.org/obo/GO_0016246 |
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altLabel |
posttranscriptional gene silencing by siRNA RNAi |
|
definition |
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. |
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hasOBONamespace |
biological_process |
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id |
GO:0016246 |
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notation |
GO:0016246 |
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prefLabel |
RNA interference |
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relatedMatch |
Wikipedia:RNA_interference |
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subClassOf |