Gene Expression Ontology

Last uploaded: December 16, 2015
Preferred Name

SAGA complex
Synonyms

Spt-Ada-Gcn5-acetyltransferase complex

Definitions

A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof - additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20|Ada5, which interact with the TATA-binding protein (TBP) - the Ada group, consisting of Ada1, Ada2, Ada3, Ada4|Gcn5, and Ada5|Spt20, which is functionally linked to the nucleosomal HAT activity - Tra1, an ATM|PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters - the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery.

ID

http://purl.obolibrary.org/obo/GO_0000124

altLabel

Spt-Ada-Gcn5-acetyltransferase complex

definition

A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof - additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20|Ada5, which interact with the TATA-binding protein (TBP) - the Ada group, consisting of Ada1, Ada2, Ada3, Ada4|Gcn5, and Ada5|Spt20, which is functionally linked to the nucleosomal HAT activity - Tra1, an ATM|PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters - the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery.

hasOBONamespace

cellular_component

id

GO:0000124

notation

GO:0000124

prefLabel

SAGA complex

subClassOf

http://purl.obolibrary.org/obo/GO_0070461

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