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Gene Expression Ontology
Preferred Name | SAGA complex | |
Synonyms |
Spt-Ada-Gcn5-acetyltransferase complex |
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Definitions |
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof - additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20|Ada5, which interact with the TATA-binding protein (TBP) - the Ada group, consisting of Ada1, Ada2, Ada3, Ada4|Gcn5, and Ada5|Spt20, which is functionally linked to the nucleosomal HAT activity - Tra1, an ATM|PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters - the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery. |
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ID |
http://purl.obolibrary.org/obo/GO_0000124 |
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altLabel |
Spt-Ada-Gcn5-acetyltransferase complex
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definition |
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof - additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20|Ada5, which interact with the TATA-binding protein (TBP) - the Ada group, consisting of Ada1, Ada2, Ada3, Ada4|Gcn5, and Ada5|Spt20, which is functionally linked to the nucleosomal HAT activity - Tra1, an ATM|PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters - the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery.
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hasOBONamespace |
cellular_component
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id |
GO:0000124
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notation |
GO:0000124
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prefLabel |
SAGA complex
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subClassOf |
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