Fission Yeast Phenotype Ontology

Last uploaded: March 27, 2024
Preferred Name

methotrexate

Synonyms

METHOTREXATE

Methotrexate

N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid

methotrexate

4-amino-N(10)-methylpteroylglutamic acid

methotrexatum

metotrexato

N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

4-amino-10-methylfolic acid

Ledertrexate

Emtexate

MTX

Rheumatrex

Trexall

ID

http://purl.obolibrary.org/obo/CHEBI_44185

charge

0

database_cross_reference

Patent:US2512572

Beilstein:70669

KEGG:D00142

LINCS:LSM-5690

DrugBank:DB00563

KEGG:C01937

PDBeChem:MTX

Drug_Central:1751

CAS:59-05-2

Wikipedia:Methotrexate

formula

C20H22N8O5

has functional parent

http://purl.obolibrary.org/obo/CHEBI_16015

has role

http://purl.obolibrary.org/obo/CHEBI_35705

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_50683

http://purl.obolibrary.org/obo/CHEBI_59517

http://purl.obolibrary.org/obo/CHEBI_50177

http://purl.obolibrary.org/obo/CHEBI_50691

http://purl.obolibrary.org/obo/CHEBI_35842

has_alternative_id

CHEBI:44183

CHEBI:6837

has_exact_synonym

METHOTREXATE

Methotrexate

N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid

has_obo_namespace

chebi_ontology

has_related_synonym

methotrexate

4-amino-N(10)-methylpteroylglutamic acid

methotrexatum

metotrexato

N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

4-amino-10-methylfolic acid

Ledertrexate

Emtexate

MTX

Rheumatrex

Trexall

id

CHEBI:44185

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1

inchikey

FBOZXECLQNJBKD-ZDUSSCGKSA-N

is conjugate acid of

http://purl.obolibrary.org/obo/CHEBI_50680

label

methotrexate

mass

454.43960

monoisotopicmass

454.17132

notation

CHEBI:44185

prefLabel

methotrexate

smiles

CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

subClassOf

http://purl.obolibrary.org/obo/CHEBI_26373

http://purl.obolibrary.org/obo/CHEBI_29347

http://purl.obolibrary.org/obo/CHEBI_35692

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_44185 OBA SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 HOIP SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 TXPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 OBA SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_44185 OBA LOOM
http://purl.bioontology.org/ontology/SNMI/C-78170 SNMI LOOM
http://www.semanticweb.org/dellvostro3750/ontologies/2018/2/untitled-ontology-10#methotrexate HP_O LOOM
http://purl.bioontology.org/ontology/MESH/D008727 MESH LOOM
http://purl.bioontology.org/ontology/ATC/L01BA01 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_44185 ODNAE LOOM
http://bmi.utah.edu/ontologies/peontology/C0025677 RAO LOOM
http://purl.obolibrary.org/obo/OMIT_0009786 OMIT LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02537 MIO LOOM
http://purl.jp/bio/4/id/200906002710798892 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/L04AX03 ATC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041719 PDQ LOOM
http://purl.bioontology.org/ontology/RCD/h34.. RCD LOOM
http://stirdf.jst.go.jp/id/200907053089575288 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4019828 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/LP16198-1 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C642 BERO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147916 ODAE LOOM
http://www.drugbank.ca/drugs/DB00563 FTC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C642 NCIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017772 PMAPP-PMO LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00469 COID LOOM
http://purl.bioontology.org/ontology/CSP/1175-1202 CRISP LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025677 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.733.631.192.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8044 OCHV LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_44185 NPO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147916 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/LA14339-8 LOINC LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00181 OCIMIDO LOOM
http://purl.obolibrary.org/obo/ARO_3007096 ARO LOOM
http://localhost/plosthes.2017-1#5614 PLOSTHES LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008727 RH-MESH LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassb1cefdd0_4663_4764_90f3_d06fe0ae1d37 WWECA LOOM
https://go.drugbank.com/drugs/DB00563 MDM LOOM
http://purl.bioontology.org/ontology/NDDF/002644 NDDF LOOM
http://purl.obolibrary.org/obo/MESH_D008727 BERO LOOM
http://purl.obolibrary.org/obo/dinto_1762 DINTO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387381009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RXNORM/6851 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005020 LOINC LOOM
http://ontology.lst.tfo.upm.es/SPT/chemo#Cancer_Therapy_Agent_Name@@9 HENEGEO LOOM
http://www.gamuts.net/entity#methotrexate GAMUTS LOOM
http://scai.fraunhofer.de/MSOntology#Methotrexate MSO LOOM
http://www.co-ode.org/ontologies/galen#Methotrexate GALEN LOOM