loading...| Preferred Name |
hemophagocytic lymphohistiocytosis |
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| Synonyms |
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| Definitions |
A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. |
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| ID |
http://purl.obolibrary.org/obo/DOID_0050120 |
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| definition |
A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. |
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| label |
hemophagocytic lymphohistiocytosis |
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| prefixIRI |
DOID:0050120 |
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| prefLabel |
hemophagocytic lymphohistiocytosis |
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| subClassOf |