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EpilepsyOntology
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November 8, 2021
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| Id | http://purl.obolibrary.org/obo/UBERON_0002037
http://purl.obolibrary.org/obo/UBERON_0002037
|
|---|---|
| Preferred Name | cerebellum |
| Definitions |
Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].
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| Synonyms |
parencephalon
corpus cerebelli
infratentorial region
epencephalon-1
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
cerebellum
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|---|---|
| prefLabel |
cerebellum
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| database_cross_reference |
UMLS:C1268981
AAO:0010485
ZFA:0000100
EHDAA2:0000232
NCIT:C12445
EMAPA:17787
CALOHA:TS-0125
BTO:0000232
MIAA:0000110
XAO:0003098
OpenCyc:Mx4rvl1eipwpEbGdrcN5Y29ycA
VHOG:0000024
MAT:0000110
UMLS:C0007765
BIRNLEX:1489
TAO:0000100
MESH:D002531
EFO:0000327
BAMS:CB
BAMS:Cb
BM:CB
DHBA:10656
EV:0100293
FMA:67944
GAID:595
HBA:4696
MA:0000198
MBA:512
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|
| notation |
UBERON:0002037
|
| in subset | |
| fromESSO |
true
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| depicted by | |
| oboInOwl:hasRelatedSynonym |
parencephalon
corpus cerebelli
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| id |
UBERON:0002037
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| has_obo_namespace |
uberon
|
| external_ontology_notes |
almost all AOs agree that the cerebellum is part of the hindbrain (sometimes specifically part of the metencephalon, which, when present, is part of the hindbrain). However, ABA has cerebellum and brain stem as partof siblings, with the hindbrain part of the brainstem
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| has_relational_adjective |
cerebellar
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| taxon_notes |
The absence of a cerebellum in hagfishes and lampreys appears to be the only exception [to the rule that vertebrates possess the same number of brain divisions]. Both hagfishes and lampreys do possess a thin band of cells located medial to the lateral line centers of the medulla (Ronan and Northcutt, 1998), which has been interpreted as a primitive cerebellum (Larsell, 1967), but more recent experimental studies (Kishida et al., 1987; Weigle and Northcutt, 1998) fail to support Larsell's claim[http://icb.oxfordjournals.org/content/42/4/743.full]
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| external_definition |
Specialized brain region derived from the dorsal metencephalon (anterior hindbrain, and perhaps including posterior midbrain) and becoming distinctive late in the segmentation period. Kimmel et al, 1995.[TAO]
Dorsal part of the hindbrain that coordinates muscle movement, posture, and balance.[AAO]
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| homology_notes |
However, although the lamprey possesses a region comparable to the cerebellum and display expression of LjFgf8/17 at the MHB (midbrain hindbrain boundary), it does not have Purkinje cells and cerebellar nuclei, as well as components of the rhombic lip-derived cerebellar and pre-cerebellar systems. It is noteworthy that the latter structures require specific expression of Pax6 in the rhombic lip of the gnathostome hindbrain. Interestingly, the lamprey rhombic lip does not express Pax6. Thus, it is tempting to speculate that in vertebrate evolution the rostral hindbrain is incapable of differentiating into the cerebellum before the co-option of Pax6 in that region. In other words, cerebellum has been brought about as an evolutionary innovation in gnathostomes, based on exaptation of MHB, rhombic lip, and some regulatory gene expression already present in the vertebrate common ancestor.[well established][VHOG]
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| 文本定义 |
Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].
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| present_in_taxon | |
| dubious_for_taxon | |
| subClassOf | |
| imported from | |
| type | |
| has_broad_synonym |
infratentorial region
|
| has exact synonym |
epencephalon-1
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