loading...| Preferred Name |
Upper motor neuron dysfunction |
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| Synonyms |
Corticospinal tract dysfunction Pyramidal tract dysfunction |
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| Definitions |
A functional deficit of the tract that conveys nervous impulses from the motor cortex of the brain to the spinal cord. The corticospinal tract mediates discrete voluntary skilled movements. Clinical features of corticospinal tract dysfunction may include spasticity and weakness, particularly affecting the lower limbs, as well as hyperreflexia, clonus at the ankles and knees, and extensor plantar responses (Babinski response). A functional anomaly of the upper motor neuron. The upper motor neurons are neurons of the primary motor cortex which project to the brainstem and spinal chord via the corticonuclear, corticobulbar and corticospinal (pyramidal) tracts. They are involved in control of voluntary movements. Dysfunction leads to weakness, impairment of fine motor movements, spasticity, hyperreflexia and abnormal pyramidal signs. |
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| ID |
http://purl.obolibrary.org/obo/HP_0002493 |
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| comment |
A functional deficit of the tract that conveys nervous impulses from the motor cortex of the brain to the spinal cord. The corticospinal tract mediates discrete voluntary skilled movements. Clinical features of corticospinal tract dysfunction may include spasticity and weakness, particularly affecting the lower limbs, as well as hyperreflexia, clonus at the ankles and knees, and extensor plantar responses (Babinski response). |
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| database_cross_reference |
UMLS:C1839042 UMLS:C1504405 |
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| has exact synonym |
Corticospinal tract dysfunction Pyramidal tract dysfunction |
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| has_obo_namespace |
human_phenotype |
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| id |
HP:0002493 |
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| imported from | ||
| label |
Upper motor neuron dysfunction |
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| notation |
HP:0002493 |
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| prefLabel |
Upper motor neuron dysfunction |
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| 文本定义 |
A functional anomaly of the upper motor neuron. The upper motor neurons are neurons of the primary motor cortex which project to the brainstem and spinal chord via the corticonuclear, corticobulbar and corticospinal (pyramidal) tracts. They are involved in control of voluntary movements. Dysfunction leads to weakness, impairment of fine motor movements, spasticity, hyperreflexia and abnormal pyramidal signs. |
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| subClassOf |