EpilepsyOntology - G protein-coupled receptor signaling pathway - Classes | NCBO BioPortal

EpilepsyOntology

Last uploaded: November 8, 2021

Id	http://purl.obolibrary.org/obo/GO_0007186 http://purl.obolibrary.org/obo/GO_0007186
Preferred Name	G protein-coupled receptor signaling pathway
Definitions	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
Synonyms	dimeric G-protein coupled receptor signalling pathway G-protein coupled receptor signaling pathway via GPCR dimer dimeric G-protein coupled receptor signaling pathway GPCR signalling pathway G protein coupled receptor protein signalling pathway G-protein-coupled receptor protein signalling pathway G-protein coupled receptor protein signal transduction G protein coupled receptor protein signaling pathway GPCR signaling pathway G-protein coupled receptor signalling pathway G-protein coupled receptor protein signaling pathway See more See less
Type	http://www.w3.org/2002/07/owl#Class

label	G protein-coupled receptor signaling pathway
prefLabel	G protein-coupled receptor signaling pathway
database_cross_reference	MIPS_funcat:30.05.02.24 MIPS_funcat:30.01.05.05
notation	GO:0007186
in subset	http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_drosophila
hasDbXRef	https://www.ncbi.nlm.nih.gov/pubmed/26721354
has_narrow_synonym	dimeric G-protein coupled receptor signalling pathway G-protein coupled receptor signaling pathway via GPCR dimer dimeric G-protein coupled receptor signaling pathway
id	GO:0007186
fromPubMed	true
has_obo_namespace	biological_process
文本定义	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
subClassOf	http://purl.obolibrary.org/obo/GO_0007165
imported from	http://purl.obolibrary.org/obo/go.owl
has_alternative_id	GO:0038042
type	http://www.w3.org/2002/07/owl#Class
has exact synonym	GPCR signalling pathway G protein coupled receptor protein signalling pathway G-protein-coupled receptor protein signalling pathway G-protein coupled receptor protein signal transduction G protein coupled receptor protein signaling pathway GPCR signaling pathway G-protein coupled receptor signalling pathway G-protein coupled receptor protein signaling pathway See more See less

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Add NCBO Web Widgets to your site for EPIO

Widget type	Widget demonstration
Jump To Type a class name from EPIO and jump to it in BioPortal Get code	Step 2: Follow the Instructions Download the quick_jump.js file and put it on your server Copy the code below and paste it to your HTML page Note: If you would like to use Quick Jump across multiple ontologies: You can enter a comma-separated list of ontology ids: var BP_ontology_id = "NCIt,SNOMEDCT"; You can set the variable to 'all' to search all ontologies in BioPortal: var BP_ontology_id = "all"; To include definitions in the Jump To drop-down, add the following variable in Javascript: var BP_include_definitions = true; In the code that you just pasted, make sure to change the path to the quick_jump.js file to point to the location where you put the file (relative to your HTML file) For example, if you put the quick_jump.js file in the same directory as your HTML file, this is the code you would use: <div id="bp_quick_jump"></div> <script type="text/javascript"> var BP_ontology_id = "EPIO";</script> <script src="quick_jump.js" type="text/javascript" charset="utf-8"></script> For more help visit NCBO Widget Wiki
Form Autocomplete Fill your form fields with classes from EPIO Get code	Example 1 (start typing the class name to get its full URI) Example 2 (get the ID for a class) Example 3 (get the preferred name for a class) Step 2: Follow the Instructions Download the form_complete.js file and put it on your server. In the header for the page where you want the form field, include the form_complete.js file. On your form, for the fields where you want to use the class-selection widget, specify the field's class in the following format: `bp_form_complete-{ontology_id_list}-{value}` For example, `bp_form_complete-NCIT-uri` will use NCI Thesaurus (ontology id is NCIT) and will put the class URI in the field after the user selects the class from the pull-down list. Note: In addition to single ontology ids, you can use a list: `bp_form_complete-NCIT,NCBITAXON-uri` OR use 'all' to search across all BioPortal ontologies: `bp_form_complete-all-uri` The autocomplete widget accesses ontology content from the latest version of the ontology. You can use the following parameters to select which value will be placed into the user-visible input field: `uri` put the complete URI of the class (e.g., http://purl.obolibrary.org/obo/NCIT_C127816 ) `shortid` put the short id of the class, as used in BioPortal (e.g., "Common_Neoplasm"); `name` put the preferred name of the class (e.g., "Common Neoplasm"); In addition to the input element you defined, there are four hidden form elements that are created and then set when a user selects a class from the list. For example, if you create a field with this code: <input type="text" name="a" class="bp_form_complete-all-uri" size="100"/> The 'name' attribute is used to create the four following fields (note how the 'a' from the name attribute is appended to the id attribute): <input type="hidden" id="a_bioportal_preferred_name"> <input type="hidden" id="a_bioportal_concept_id"> <input type="hidden" id="a_bioportal_ontology_id"> <input type="hidden" id="a_bioportal_full_id"> Additional parameters are documented on the NCBO Widget Wiki For more help visit NCBO Widget Wiki
Visualization Display a visualization for a given class in EPIO Get code	Step 2: Follow the Instructions Copy the code below and paste it to your HTML page <iframe frameborder="0" src="/widgets/visualization?ontology=EPIO&class=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FNCIT_C127816&apikey=YOUR_API_KEY"></iframe> For more help visit NCBO Widget Wiki
Tree Widget Display a class tree with a search field for EPIO Get code	Step 2: Follow the Instructions Copy the code below and paste it to your HTML page <link rel="stylesheet" type="text/css" href="/widgets/jquery.ncbo.tree.css"> <script src="/widgets/jquery.ncbo.tree-2.0.2.js"></script> <div id="widget_tree"></div> var widget_tree = $("#widget_tree").NCBOTree({ apikey: "YOUR_API_KEY", ontology: "EPIO" }); You can also view a detailed demonstration For more help visit NCBO Widget Wiki