loading...| Preferred Name | subcortical band heterotopia | |
| Synonyms |
band heterotopia subcortical laminar heterotopia double cortex syndrome heterotopic cortex HeCo |
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| Definitions |
A congenital nervous system abnormality characterized by migration of neurons to ectopic locations in the brain where the neurons form areas that appear as band-like clusters of white tissue underneath the gray tissue of the cerebral cortex. |
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| ID |
http://purl.obolibrary.org/obo/DOID_0111169 |
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| database_cross_reference |
MESH:D054221 UMLS_CUI:C1848201 OMIM:600348 NCI:C116933 ORDO:99796 |
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| fromILAE |
true |
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| has exact synonym |
band heterotopia subcortical laminar heterotopia double cortex syndrome heterotopic cortex HeCo |
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| has_obo_namespace |
disease_ontology |
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| hasDefinition |
Subcortical band heterotopia is a malformation of cortical development, where there is a band of cortical cells (grey matter) located between the lateral ventricular wall and the cortex. The overlying cortex has a largely normal appearance, but may have mildly shallow sulcation. It occurs due to failure of migration of a population of neuronal cells to their correct location in the cerebral cortex. Subcortical band heterotopia is typically bilateral, symmetric and anterior-predominant.Occasionally subcortical band heterotopia can be bifrontal only, or rarely biparieto-occipital. Subcortical band heterotopia usually occurs in isolation, without other associated structural brain abnormalities, though mild cerebellar hypoplasia can occur with DCX mutations. |
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| id |
DOID:0111169 |
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| imported from | ||
| in subset | ||
| label |
subcortical band heterotopia |
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| notation |
DOID:0111169 |
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| prefLabel |
subcortical band heterotopia |
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| 文本定义 |
A congenital nervous system abnormality characterized by migration of neurons to ectopic locations in the brain where the neurons form areas that appear as band-like clusters of white tissue underneath the gray tissue of the cerebral cortex. |
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| subClassOf |