Experimental Factor Ontology

Last uploaded: March 18, 2024
Preferred Name

naproxen

Synonyms

naproxen

Naproxen

(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid

naproxeno

(S)-2-(6-Methoxy-2-naphthyl)propanoic acid

(+)-Naproxen

(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid

(+)-2-(Methoxy-2-naphthyl)-propionsaeure

(S)-2-(6-Methoxy-2-naphthyl)propionic acid

(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid

(+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid

naproxenum

naproxene

(+)-(S)-Naproxen

(+)-2-(6-Methoxy-2-naphthyl)propionic acid

(S)-Naproxen

(S)-(+)-Naproxen

(+)-2-(Methoxy-2-naphthyl)-propionic acid

Definitions

A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes.

ID

http://purl.obolibrary.org/obo/CHEBI_7476

charge

0

database_cross_reference

Wikipedia:Naproxen

Patent:US4009197

KEGG:D00118

Drug_Central:1883

DrugBank:DB00788

PMID:18044350

CAS:22204-53-1

Beilstein:3591067

PMID:24478225

Patent:US3904682

PMID:9784154

LINCS:LSM-5689

HMDB:HMDB0001923

definition

A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes.

formula

C14H14O3

has_alternative_id

CHEBI:603695

has_exact_synonym

naproxen

Naproxen

(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid

has_obo_namespace

chebi_ontology

has_related_synonym

naproxeno

(S)-2-(6-Methoxy-2-naphthyl)propanoic acid

naproxen

(+)-Naproxen

(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid

(+)-2-(Methoxy-2-naphthyl)-propionsaeure

(S)-2-(6-Methoxy-2-naphthyl)propionic acid

(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid

(+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid

naproxenum

naproxene

(+)-(S)-Naproxen

(+)-2-(6-Methoxy-2-naphthyl)propionic acid

(S)-Naproxen

(S)-(+)-Naproxen

(+)-2-(Methoxy-2-naphthyl)-propionic acid

id

CHEBI:7476

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1

inchikey

CMWTZPSULFXXJA-VIFPVBQESA-N

label

naproxen

mass

230.25920

monoisotopicmass

230.09429

notation

CHEBI:7476

prefLabel

naproxen

smiles

COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O

subClassOf

http://purl.obolibrary.org/obo/CHEBI_24431

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http://purl.obolibrary.org/obo/CHEBI_7476 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7476 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7476 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7476 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7476 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7476 CHEBI SAME_URI
http://purl.obolibrary.org/obo/XCO_0001193 XCO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040222 PDQ LOOM
http://purl.bioontology.org/ontology/SNMI/C-60410 SNMI LOOM
http://purl.bioontology.org/ontology/VANDF/4018847 VANDF LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Naproxen STMSO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016946 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372588000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/M02AA12 ATC LOOM
http://purl.obolibrary.org/obo/NCIT_C680 BERO LOOM
http://purl.bioontology.org/ontology/RCD/j2c.. RCD LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00347 COID LOOM
http://scai.fraunhofer.de/AlzheimerOntology#naproxen ADO LOOM
http://bmi.utah.edu/ontologies/peontology/C0027396 RAO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.638.472.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_7476 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7476 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_7476 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7476 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_7476 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7476 CHEBI LOOM
http://www.co-ode.org/ontologies/galen#Naproxen GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009288 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP16215-3 LOINC LOOM
http://purl.bioontology.org/ontology/ATC/G02CC02 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147149 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU015374 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0027396 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0010322 OMIT LOOM
https://go.drugbank.com/drugs/DB00788 MDM LOOM
http://purl.bioontology.org/ontology/MESH/D009288 MESH LOOM
http://purl.jp/bio/4/id/200906020191518869 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/4001-0089 CRISP LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C680 NCIT LOOM
http://purl.bioontology.org/ontology/RXNORM/7258 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/002380 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8483 OCHV LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:03045 MIO LOOM
http://doe-generated-ontology.com/OntoAD#C0027396 ONTOAD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.638.472.450 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/M01AE02 ATC LOOM
http://stirdf.jst.go.jp/id/200907067016753227 IOBC LOOM
http://purl.obolibrary.org/obo/MESH_D009288 BERO LOOM
http://www.drugbank.ca/drugs/DB00788 FTC LOOM