Experimental Factor Ontology

Last uploaded: November 20, 2019
Preferred Name

ciprofloxacin

Synonyms

1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID

1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

ciprofloxacine

InChIKey=MYSWGUAQZAJSOK-MPIMZMORCO

ciprofloxacinum

ciprofloxacino

ciproxin; cipro

1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

InChI=1/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)/f/h23H

1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid

"Blue Bone" Formation

ABL1

1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

C17H18FN3O3

v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene

1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

ABL1 Gene

OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O

Definitions

This gene is involved in cell adhesion, differentiation, division and stress response. Quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. A second generation fluoroquinolone antibacterial, it works by interfering with the enzymes that cause DNA to rewind after being copied, so stopping DNA and protein synthesis.

ID

http://purl.obolibrary.org/obo/CHEBI_100241

database_cross_reference

SNOMEDCT:372840008

NCIt:C375

MSH:D002939

SNOMEDCT:7577004

definition

This gene is involved in cell adhesion, differentiation, division and stress response.

Quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. A second generation fluoroquinolone antibacterial, it works by interfering with the enzymes that cause DNA to rewind after being copied, so stopping DNA and protein synthesis.

definition_citation

1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid

2824

22824

C17H18FN3O3

85721-33-1

has_exact_synonym

1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID

1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

ciprofloxacine

InChIKey=MYSWGUAQZAJSOK-MPIMZMORCO

ciprofloxacinum

ciprofloxacino

ciproxin; cipro

1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

InChI=1/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)/f/h23H

1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid

"Blue Bone" Formation

ABL1

1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

C17H18FN3O3

v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene

1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

ABL1 Gene

OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O

has_role

http://purl.obolibrary.org/obo/CHEBI_36047

label

ciprofloxacin

prefixIRI

CHEBI:100241

prefLabel

ciprofloxacin

subClassOf

http://purl.obolibrary.org/obo/CHEBI_23888

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http://purl.bioontology.org/ontology/UATC/J01MA02 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100241 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 MCO SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C375 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C375 NCIT LOOM
http://purl.bioontology.org/ontology/CSP/5004-0016 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002939 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907004431328874 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147503 NDFRT LOOM
http://purl.bioontology.org/ontology/UATC/S03AA07 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372840008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-55710 SNMI LOOM
https://bioportal.bioontology.org/ontologies/DMTO.owl#DMTO_0001799 DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.186 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP15380-6 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Ciprofloxacin GALEN LOOM
http://purl.obolibrary.org/obo/ARO_0000036 ARO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040784 PDQ LOOM
http://purl.bioontology.org/ontology/NDDF/002882 NDDF LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147503 ODAE LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#DMTO_0001799 FASTO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004599 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/S01AE03 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008809 OCHV LOOM
http://purl.jp/bio/4/id/200906033484858081 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D002939 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/2551 RXNORM LOOM
http://purl.bioontology.org/ontology/VANDF/4019307 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3001 OCHV LOOM
http://www.drugbank.ca/drugs/DB00537 FTC LOOM
http://purl.bioontology.org/ontology/UATC/S02AA15 ATC LOOM