Preferred Name | autoimmune thyroid disease | |
Synonyms |
autoimmune thyroiditis lymphomatous thyroiditis lymphocytic thyroiditis thyroiditides, lymphocytic thyroiditides, lymphomatous lymphocytic thyroiditides thyroiditides, autoimmune autoimmune thyroiditides thyroiditis, lymphomatous thyroiditis, lymphocytic lymphomatous thyroiditides autoimmune thyroid disease Thyroiditides, Autoimmune autoimmune thyroid gland inflammation Autoimmune Thyroiditis Autoimmune Thyroiditides |
|
Definitions |
a disease in which the body interprets the thyroid glands and its hormone products T3, T4 and TSH as threats, therefore producing special antibodies that target the thyroid’s cells, thereby destroying it. It presents with hypothyroidism or hyperthyroidism and the presence or absence of goiters. Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis. Disease of the thyroid gland due to autoimmunity in which the patient's immune system attacks and damages their thyroid. It can be either hyper- or hypothyroidism. (http://www.medicinenet.com/script/main/art.asp?articlekey=24314 - accessed 20th July, 2015) |
|
ID |
http://www.ebi.ac.uk/efo/EFO_0006812 |
|
comment |
Disease of the thyroid gland due to autoimmunity in which the patient's immune system attacks and damages their thyroid. It can be either hyper- or hypothyroidism. (http://www.medicinenet.com/script/main/art.asp?articlekey=24314 - accessed 20th July, 2015) |
|
database_cross_reference |
Wikipedia:Autoimmune_thyroiditis MONDO:0005623 SNOMEDCT:66944004 UMLS:C0920350 MESH:D013967 MeSH:D013967 MEDGEN:183088 MedDRA:10049046 DOID:7188 |
|
definition |
a disease in which the body interprets the thyroid glands and its hormone products T3, T4 and TSH as threats, therefore producing special antibodies that target the thyroid’s cells, thereby destroying it. It presents with hypothyroidism or hyperthyroidism and the presence or absence of goiters. Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis. |
|
gwas_trait |
true |
|
has_exact_synonym |
autoimmune thyroid disease autoimmune thyroiditis Thyroiditides, Autoimmune autoimmune thyroid gland inflammation Autoimmune Thyroiditis Autoimmune Thyroiditides |
|
has_related_synonym |
autoimmune thyroiditis lymphomatous thyroiditis lymphocytic thyroiditis thyroiditides, lymphocytic thyroiditides, lymphomatous lymphocytic thyroiditides thyroiditides, autoimmune autoimmune thyroiditides thyroiditis, lymphomatous thyroiditis, lymphocytic lymphomatous thyroiditides |
|
id |
EFO:0006812 |
|
in_subset | ||
label |
autoimmune thyroid disease |
|
notation |
EFO:0006812 |
|
preferred label |
autoimmune thyroid disease |
|
prefLabel |
autoimmune thyroid disease |
|
skos_exactMatch |
http://purl.obolibrary.org/obo/EFO_0006812 http://identifiers.org/medgen/183088 |
|
term editor |
Sirarat Sarntivijai |
|
subClassOf |
http://purl.obolibrary.org/obo/MONDO_0000569 http://www.ebi.ac.uk/efo/EFO_0005809 |