Experimental Factor Ontology - gastroesophageal reflux disease - Classes | NCBO BioPortal

Experimental Factor Ontology

Last uploaded: February 17, 2025

Id	http://www.ebi.ac.uk/efo/EFO_0003948 http://www.ebi.ac.uk/efo/EFO_0003948
Preferred Name	gastroesophageal reflux disease
Definitions	Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa.
Synonyms	gastroesophageal reflux, pediatric gastroesophageal reflux, paediatric ger Gastro-Esophageal Reflux Reflux, Gastro-oesophageal acid reflux Gastro-oesophageal Reflux Gastro oesophageal Reflux gastroesophageal reflux disease GASTROESOPHAGEAL REFLUX DIS Gastresophageal reflux Reflux, Gastroesophageal Gastroesophageal Reflux GERD - gastro-esophageal reflux disease Reflux, Gastro-Esophageal gastroesophageal reflux Esophageal Reflux Gastro Esophageal Reflux gastro-esophageal reflux GERD reflux See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa.
preferred label	gastroesophageal reflux disease
label	gastroesophageal reflux disease
prefLabel	gastroesophageal reflux disease
exactMatch	http://identifiers.org/snomedct/235595009 http://identifiers.org/medgen/6553 http://identifiers.org/mesh/D005764 http://purl.obolibrary.org/obo/NCIT_C26781 https://omim.org/entry/109350 http://linkedlifedata.com/resource/umls/id/C0017168 http://purl.obolibrary.org/obo/DOID_8534 http://www.ebi.ac.uk/efo/EFO_0003948 See more See less
database_cross_reference	MeSH:D005764 NCIt:C26781 MedDRA:10038262 SCTID:235595009 MONDO:0007186 NCIT:C26781 MedDRA:10066874 SNOMEDCT:235595009 UMLS:C0017168 ICD9:530.81 OMIM:109350 MEDGEN:6553 MESH:D005764 DOID:8534 HP:0002020 ICD10:K21 See more See less
notation	EFO:0003948
in_subset	http://purl.obolibrary.org/obo/mondo#otar
term editor	Tomasz Adamusiak
has_related_synonym	gastroesophageal reflux, pediatric gastroesophageal reflux, paediatric ger
id	EFO:0003948
gwas_trait	true
subClassOf	http://www.ebi.ac.uk/efo/EFO_0000508 http://www.ebi.ac.uk/efo/EFO_0009608 http://www.ebi.ac.uk/efo/EFO_0009544
type	http://www.w3.org/2002/07/owl#Class
has_exact_synonym	Gastro-Esophageal Reflux Reflux, Gastro-oesophageal acid reflux Gastro-oesophageal Reflux Gastro oesophageal Reflux gastroesophageal reflux disease GASTROESOPHAGEAL REFLUX DIS Gastresophageal reflux Reflux, Gastroesophageal Gastroesophageal Reflux GERD - gastro-esophageal reflux disease Reflux, Gastro-Esophageal gastroesophageal reflux Esophageal Reflux Gastro Esophageal Reflux gastro-esophageal reflux GERD reflux See more See less

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