Experimental Factor Ontology

Last uploaded: July 4, 2024
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Preferred Name

protein array
Synonyms

protein binding array
Definitions

A protein array is an array which provides a multiplex approach to identify protein-protein interactions, to identify the substrates of protein kinases, to identify transcription factor protein-activation, or to identify the targets of biologically active small molecules. The array is a substrate (e.g. glass) on which different molecules of protein or specific DNA binding sequences (as capture probes for the proteins) have been affixed at separate locations in an ordered manner thus forming a microscopic array. The most common protein microarray is the antibody microarray, where antibodies are spotted onto the protein chip and are used as capture molecules to detect proteins from cell lysate solutions.
ID

http://www.ebi.ac.uk/efo/EFO_0002702
created_by

Helen Parkinson
creator

Helen Parkinson
definition

A protein array is an array which provides a multiplex approach to identify protein-protein interactions, to identify the substrates of protein kinases, to identify transcription factor protein-activation, or to identify the targets of biologically active small molecules. The array is a substrate (e.g. glass) on which different molecules of protein or specific DNA binding sequences (as capture probes for the proteins) have been affixed at separate locations in an ordered manner thus forming a microscopic array. The most common protein microarray is the antibody microarray, where antibodies are spotted onto the protein chip and are used as capture molecules to detect proteins from cell lysate solutions.
definition_citation

http://en.wikipedia.org/wiki/Protein_microarray
has_exact_synonym

protein binding array
label

protein array
preferred label

protein array
prefixIRI

efo1:EFO_0002702
prefLabel

protein array
subClassOf

http://www.ebi.ac.uk/efo/EFO_0002698
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