loading...| Preferred Name | obsolete_Parkinson's disease | |
| Synonyms |
IDIOPATHIC PARKINSON DIS Lewy Body Parkinson Disease Idiopathic Parkinson Disease PARKINSON DIS IDIOPATHIC PARKINSON DIS Parkinson's syndrome Parkinson syndrome Primary Parkinsonism Parkinson disease Parkinson's disease NOS (disorder) IDIOPATHIC PARKINSONS DIS Parkinson's Parkinson's disease (disorder) PARKINSONS DIS LEWY BODY PARKINSON DIS Parkinsons disease PARKINSONS DIS LEWY BODY Idiopathic PD Parkinsonism, Primary Parkinson Disease, Idiopathic Idiopathic Parkinson's Disease Parkinson's disease NOS Parkinson's Disease, Lewy Body Parkinsonian disorder Paralysis agitans Lewy Body Parkinson's Disease PARKINSONS DIS IDIOPATHIC Parkinson's Disease, Idiopathic Parkinsons |
|
| Definitions |
A neurodegenerative disease that results_from degeneration of the central nervous system that often impairs the sufferer's motor skills, speech, and other functions. A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0002508 |
|
| Obsolete |
true |
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| database_cross_reference |
NIFSTD:birnlex_2098 SNOMEDCT:49049000 MedDRA:10061536 MeSH:D010300 OMIM:168600 OMIM:616361 NCIt:C26845 OMIM:616710 DOID:14330 ICD10:G20 ICD9:332 |
|
| definition |
A neurodegenerative disease that results_from degeneration of the central nervous system that often impairs the sufferer's motor skills, speech, and other functions. A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
|
| deprecated |
true |
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| has_exact_synonym |
IDIOPATHIC PARKINSON DIS Lewy Body Parkinson Disease Idiopathic Parkinson Disease PARKINSON DIS IDIOPATHIC PARKINSON DIS Parkinson's syndrome Parkinson syndrome Primary Parkinsonism Parkinson disease Parkinson's disease NOS (disorder) IDIOPATHIC PARKINSONS DIS Parkinson's Parkinson's disease (disorder) PARKINSONS DIS LEWY BODY PARKINSON DIS Parkinsons disease PARKINSONS DIS LEWY BODY Idiopathic PD Parkinsonism, Primary Parkinson Disease, Idiopathic Idiopathic Parkinson's Disease Parkinson's disease NOS Parkinson's Disease, Lewy Body Parkinsonian disorder Paralysis agitans Lewy Body Parkinson's Disease PARKINSONS DIS IDIOPATHIC Parkinson's Disease, Idiopathic Parkinsons |
|
| label |
obsolete_Parkinson's disease |
|
| obsoleted_in_version |
3.38.0 |
|
| organizational_class |
true |
|
| preferred label |
obsolete_Parkinson's disease |
|
| prefixIRI |
efo:EFO_0002508 |
|
| prefLabel |
obsolete_Parkinson's disease |
|
| reason_for_obsolescence |
Replaced with Mondo term see https://github.com/ebispot/efo/issues/1381 |
|
| term editor |
Tomasz Adamusiak Ele Holloway James Malone |
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| term replaced by | ||
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://www.ebi.ac.uk/efo/EFO_0002508 | CLO | SAME_URI | |
| http://www.ebi.ac.uk/efo/EFO_0002508 | CCONT | SAME_URI | |
| http://www.ebi.ac.uk/efo/EFO_0002508 | CCONT | LOOM |