loading...| Preferred Name | obsolete_Alzheimer's disease | |
| Synonyms |
Dementia in Alzheimer's disease (disorder) Alzheimer Dementia, Presenile Alzheimer's Dementia Alzheimer's disease (disorder) Disease, Alzheimer [X]Dementia in Alzheimer's disease Dementia of the Alzheimer's type AD - Alzheimer's disease Alzheimer's disease, NOS DAT - Dementia Alzheimer's type Dementia, Alzheimer Type Alzheimers disease Dementia, Presenile Dementia, Presenile Alzheimer Alzheimer Type Dementia ALZHEIMERS DIS Dementia in Alzheimer's disease, unspecified (disorder) Dementia in Alzheimer's disease Disease, Alzheimer's Alzheimer Disease Alzheimer Dementia [X]Dementia in Alzheimer's disease (disorder) Presenile Alzheimer Dementia Alzheimer's ALZHEIMER DIS sporadic Alzheimer's disease Alzheimers Dementia AD Alzheimers |
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| Definitions |
A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. A dementia that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting in late middle age and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability. A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0000249 |
|
| Obsolete |
true |
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| database_cross_reference |
MedDRA:10001896 OMIM:605526 NCIt:C34524 NIFSTD:birnlex_2092 OMIM:502500 OMIM:615590 OMIM:615711 SNOMEDCT:26929004 OMIM:104300 OMIM:608907 NCIt:C38778 SNOMEDCT:12348006 SNOMEDCT:15662003 MeSH:D000544 DOID:10652 ICD10:G30 ICD9:290.1 ICD9:331.0 NCIt:C2866 |
|
| definition |
A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. A dementia that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting in late middle age and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability. A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
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| definition_citation | ||
| deprecated |
true |
|
| has_exact_synonym |
Dementia in Alzheimer's disease (disorder) Alzheimer Dementia, Presenile Alzheimer's Dementia Alzheimer's disease (disorder) Disease, Alzheimer [X]Dementia in Alzheimer's disease Dementia of the Alzheimer's type AD - Alzheimer's disease Alzheimer's disease, NOS DAT - Dementia Alzheimer's type Dementia, Alzheimer Type Alzheimers disease Dementia, Presenile Dementia, Presenile Alzheimer Alzheimer Type Dementia ALZHEIMERS DIS Dementia in Alzheimer's disease, unspecified (disorder) Dementia in Alzheimer's disease Disease, Alzheimer's Alzheimer Disease Alzheimer Dementia [X]Dementia in Alzheimer's disease (disorder) Presenile Alzheimer Dementia Alzheimer's ALZHEIMER DIS sporadic Alzheimer's disease Alzheimers Dementia AD Alzheimers |
|
| label |
obsolete_Alzheimer's disease |
|
| obsoleted_in_version |
3.38.0 |
|
| organizational_class |
true |
|
| preferred label |
obsolete_Alzheimer's disease |
|
| prefixIRI |
efo:EFO_0000249 |
|
| prefLabel |
obsolete_Alzheimer's disease |
|
| reason_for_obsolescence |
Replaced with Mondo term see https://github.com/ebispot/efo/issues/1381 |
|
| term editor |
Tomasz Adamusiak James Malone |
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| term replaced by | ||
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://www.ebi.ac.uk/efo/EFO_0000249 | CLO | SAME_URI | |
| http://www.ebi.ac.uk/efo/EFO_0000249 | CCONT | SAME_URI | |
| http://www.ebi.ac.uk/efo/EFO_0000249 | CCONT | LOOM |