Experimental Factor Ontology

Last uploaded: July 4, 2024
Preferred Name

neoplasm of mature B-cells

Synonyms

mature B-cell neoplasms

mature B-cell neoplasm

mature B-cell lymphocytic neoplasm

neoplasm of mature B-cells

Definitions

A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). Editor note: is a non-hodgkin in ONCOTREE

ID

http://www.ebi.ac.uk/efo/EFO_0000096

comment

Editor note: is a non-hodgkin in ONCOTREE

closeMatch

http://identifiers.org/snomedct/46744002

http://identifiers.org/snomedct/40411000

http://linkedlifedata.com/resource/umls/id/CL448793

http://identifiers.org/snomedct/55150002

http://identifiers.org/snomedct/55020008

database_cross_reference

SCTID:269476000

NCIT:C27910

EFO:0000096

UMLS:C1334633

ONCOTREE:MBN

DOID:706

ICD9:202.0

NCIT:C3457

MONDO:0004949

definition

A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).

A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).

exactMatch

http://linkedlifedata.com/resource/umls/id/C1334633

http://purl.obolibrary.org/obo/NCIT_C27910

http://purl.obolibrary.org/obo/DOID_706

http://identifiers.org/snomedct/269476000

gwas_trait

true

has_exact_synonym

mature B-cell neoplasm

mature B-cell lymphocytic neoplasm

neoplasm of mature B-cells

has_related_synonym

mature B-cell neoplasms

id

EFO:0000096

in_subset

http://purl.obolibrary.org/obo/mondo/mondo-base#rare

http://purl.obolibrary.org/obo/mondo/mondo-base#otar

http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare

label

neoplasm of mature B-cells

notation

EFO:0000096

preferred label

neoplasm of mature B-cells

prefLabel

neoplasm of mature B-cells

subClassOf

http://purl.obolibrary.org/obo/MONDO_0004095

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