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Experimental Factor Ontology
| Preferred Name | neoplasm of mature B-cells | |
| Synonyms |
mature B-cell neoplasms mature B-cell neoplasm mature B-cell lymphocytic neoplasm neoplasm of mature B-cells |
|
| Definitions |
A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). Editor note: is a non-hodgkin in ONCOTREE |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0000096 |
|
| comment |
Editor note: is a non-hodgkin in ONCOTREE
|
|
| closeMatch |
http://identifiers.org/snomedct/46744002 http://identifiers.org/snomedct/40411000 http://linkedlifedata.com/resource/umls/id/CL448793 |
|
| database_cross_reference |
SCTID:269476000 NCIT:C27910 EFO:0000096 MONDO:0004949 MEDGEN:235305 UMLS:C1334633 ONCOTREE:MBN DOID:706 ICD9:202.0 NCIT:C3457
|
|
| definition |
A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
|
|
| exactMatch |
http://identifiers.org/medgen/235305 http://linkedlifedata.com/resource/umls/id/C1334633 http://purl.obolibrary.org/obo/EFO_0000096 http://purl.obolibrary.org/obo/NCIT_C27910 |
|
| gwas_trait |
true
|
|
| has_exact_synonym |
mature B-cell neoplasm mature B-cell lymphocytic neoplasm neoplasm of mature B-cells
|
|
| has_related_synonym |
mature B-cell neoplasms
|
|
| id |
EFO:0000096
|
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare |
|
| label |
neoplasm of mature B-cells
|
|
| notation |
EFO:0000096
|
|
| preferred label |
neoplasm of mature B-cells
|
|
| prefLabel |
neoplasm of mature B-cells
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
| Mapping To | Ontology | Source |
|---|---|---|
| http://www.ebi.ac.uk/efo/EFO_0000096 | CCONT | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0004949 | OBA | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0004949 | MONDO | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0004949 | DOVES | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0004949 | KTAO | LOOM |
| http://www.ebi.ac.uk/efo/EFO_0000096 | CCONT | LOOM |