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Experimental Factor Ontology
Last uploaded:
January 16, 2025
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Id | http://purl.obolibrary.org/obo/UBERON_0001040
http://purl.obolibrary.org/obo/UBERON_0001040
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Preferred Name | yolk sac |
Definitions |
A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP].
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Synonyms |
vesicula umbilicalis
saccus vitellinus
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. |
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preferred label |
yolk sac
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label |
yolk sac
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prefLabel |
yolk sac
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database_cross_reference |
EHDAA2:0002212
MESH:D015017
SCTID:362845002
CALOHA:TS-1130
VHOG:0000830
EFO:0003078
Wikipedia:Yolk_sac
BTO:0001471
UMLS:C0043425
NCIT:C14128
EMAPA:16085
EHDAA:164
FMA:87180
GAID:1301
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notation |
UBERON:0001040
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in_subset | |
editor note |
consider splitting class
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has_related_synonym |
vesicula umbilicalis
saccus vitellinus
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id |
UBERON:0001040
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has_obo_namespace |
uberon
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depiction | |
taxon_notes |
In therians, a structure homologous to the yolk sac is is present, but contains no yolk platelets. Instead it is filled with fluid [ISBN:0073040584 (Vertebrates, Kardong)]
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external_definition |
One of the extraembryonic fetal membranes that balloons out from the fetal midgut. [TFD][VHOG]
the extraembryonic tissue membrane, formed from the visceral endoderm and the extraembryonic mesoderm, which is located ventral to the embryonic disc and is connected to the presumptive midgut of the embryo; the yolk that it contains is the site of embryonic hematopoiesis and vitelline circulation is involved in early embryonic circulation; it is the origin of the primordial germ cells
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homology_notes |
Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]
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subClassOf | |
type |
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