Experimental Factor Ontology

Last uploaded: January 16, 2025
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Id http://purl.obolibrary.org/obo/UBERON_0000017
http://purl.obolibrary.org/obo/UBERON_0000017
Preferred Name

exocrine pancreas
Definitions
The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO].
Synonyms
exocrine part of pancreas
exocrine component of pancreas
pars exocrina pancreatis
exocrine pancreas
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO].
preferred label
exocrine pancreas
label
exocrine pancreas
prefLabel
exocrine pancreas
database_cross_reference
SCTID:248202004
NCIT:C32546
TAO:0001249
CALOHA:TS-1241
MESH:D046790
XAO:0000137
AAO:0010407
UMLS:C0553695
BTO:0000434
ZFA:0001249
VHOG:0000048
EMAPA:35328
Wikipedia:Exocrine_component_of_pancreas
EV:0100093
FMA:16017
MA:0002415
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notation
UBERON:0000017
in_subset
has_related_synonym
exocrine part of pancreas
exocrine component of pancreas
id
UBERON:0000017
has_obo_namespace
uberon
part_of
external_definition
The part of the pancreas that acts as an exocrine gland, consisting of the pancreatic acini, which produce pancreatic juice and secrete it into the intestine to aid in protein digestion. [TFD][VHOG]
The exocrine pancreas is composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.[TAO]
homology_notes
In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]
RO_0002175
subClassOf
type
has_exact_synonym
pars exocrina pancreatis
exocrine pancreas
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