loading...| Preferred Name |
Parkinson disease |
|
| Synonyms |
paralysis agitans Parkinson disease Parkinson's disease |
|
| Definitions |
A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression. |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0005180 |
|
| database_cross_reference |
NANDO:1200010 MESH:D010300 NIFSTD:birnlex_2098 UMLS:C0030567 Orphanet:319705 NCIT:C26845 SCTID:49049000 OMIMPS:168600 DOID:14330 ICD9:332 ICD9:332.0 |
|
| definition |
A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression. |
|
| exactMatch |
http://linkedlifedata.com/resource/umls/id/C0030567 http://purl.obolibrary.org/obo/DOID_14330 http://identifiers.org/mesh/D010300 https://omim.org/phenotypicSeries/PS168600 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
paralysis agitans Parkinson disease Parkinson's disease |
|
| id |
MONDO:0005180 |
|
| in_subset | ||
| label |
Parkinson disease |
|
| notation |
MONDO:0005180 |
|
| prefLabel |
Parkinson disease |
|
| subClassOf | ||
| excluded_subClassOf |