Link to this page
Experimental Factor Ontology
Last uploaded:
February 17, 2025
Jump to:
| Id | http://purl.obolibrary.org/obo/HP_0000256
http://purl.obolibrary.org/obo/HP_0000256
|
|---|---|
| Preferred Name | Macrocephaly |
| Definitions |
Occipitofrontal (head) circumference greater than 97th centile compared to appropriate, age matched, sex-matched normal standards. Alternatively, a apparently increased size of the cranium.
Macrocephaly can be due to hydrocephalus (increased CFSF), megalencephaly (increased brain volume) or thickening of the skull. Head circumference is measured from just above the glabella (the most prominent point on the frontal bone above the root of the nose) to the most posterior prominent point of the occipital bone using a tape measure. Some standard charts are organized by centiles [Hall et al. [2007]], others by standard deviations [Farkas, [1981]]. It is important to add an indication of how far above the normal standard the head circumference is if an accurate assessment of this can be made. Macrocephaly is an absolute term. The term relative macrocephaly can be used when the head size centile exceeds the centile for height, for example, head size at the 75th centile with height at the 5th centile for age and sex.
|
| Synonyms |
Big cranium
Large cranium
Large skull
Large calvaria
Big calvaria
Increased size of head
Big head
Big skull
Increased size of cranium
Macrocephalus
Macrocrania
Increased size of skull
Large head circumference
Megacephaly
Large head
See more
See less
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Occipitofrontal (head) circumference greater than 97th centile compared to appropriate, age matched, sex-matched normal standards. Alternatively, a apparently increased size of the cranium. |
|---|---|
| preferred label |
Macrocephaly
|
| label |
Macrocephaly
|
| comment |
Macrocephaly can be due to hydrocephalus (increased CFSF), megalencephaly (increased brain volume) or thickening of the skull. Head circumference is measured from just above the glabella (the most prominent point on the frontal bone above the root of the nose) to the most posterior prominent point of the occipital bone using a tape measure. Some standard charts are organized by centiles [Hall et al. [2007]], others by standard deviations [Farkas, [1981]]. It is important to add an indication of how far above the normal standard the head circumference is if an accurate assessment of this can be made. Macrocephaly is an absolute term. The term relative macrocephaly can be used when the head size centile exceeds the centile for height, for example, head size at the 75th centile with height at the 5th centile for age and sex.
|
| prefLabel |
Macrocephaly
|
| database_cross_reference |
UMLS:C4083076
UMLS:C4280663
UMLS:C4280664
UMLS:C4255213
Fyler:4335
|
| notation |
HP:0000256
|
| in_subset | |
| id |
HP:0000256
|
| subClassOf | |
| has_alternative_id |
HP:0005491
HP:0005496
HP:0200135
|
| type | |
| has_broad_synonym |
Big cranium
Large cranium
Large skull
Large calvaria
Big calvaria
Increased size of head
Big head
Big skull
See more
See less
|
| has_exact_synonym |
Increased size of cranium
Macrocephalus
Macrocrania
Increased size of skull
Large head circumference
Megacephaly
Large head
See more
See less
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |