Link to this page
Experimental Factor Ontology
Last uploaded:
January 16, 2025
Jump to:
| Id | http://purl.obolibrary.org/obo/CHEBI_10112
http://purl.obolibrary.org/obo/CHEBI_10112
|
|---|---|
| Preferred Name | zileuton |
| Definitions |
A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
|
| Synonyms |
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
Leutrol
Zyflo
zileuton
zileutonum
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
Zileuton
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma. |
|---|---|
| preferred label |
zileuton
|
| label |
zileuton
|
| prefLabel |
zileuton
|
| database_cross_reference |
PMID:19645854
PMID:20204486
DrugBank:DB00744
Wikipedia:Zileuton
LINCS:LSM-5084
KEGG:D00414
Drug_Central:2862
PMID:19309543
Reaxys:4869674
CAS:111406-87-2
PMID:20436887
See more
See less
|
| notation |
CHEBI:10112
|
| in_subset | |
| inchi |
InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
|
| has_related_synonym |
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
Leutrol
Zyflo
zileuton
zileutonum
See more
See less
|
| id |
CHEBI:10112
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| formula |
C11H12N2O2S
|
| subClassOf | |
| inchikey |
MWLSOWXNZPKENC-UHFFFAOYSA-N
|
| mass |
236.29126
|
| monoisotopicmass |
236.06195
|
| type | |
| smiles |
CC(N(O)C(N)=O)c1cc2ccccc2s1
|
| has_exact_synonym |
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
Zileuton
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |