loading...| Preferred Name |
Ofloxacin |
|
| Synonyms |
rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid (+-)-ofloxacin racemic ofloxacin (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid ofloxacinum rac-ofloxacin rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid DL 8280 DL-8280 Exocin Floxin Gailuoxian HOE 280 HOE-280 OFLX ORF 18489 Ocuflox Oxaldin Prifloxcin Prifloxin Tarivid Visiren ofloxacin ofloxacine ofloxacino |
|
| Definitions |
A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_7731 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:36268299 PMID:15008519 KEGG:C07321 PMID:11903499 PMID:7884650 KEGG:D00453 Wikipedia:Ofloxacin PMID:6960805 MetaCyc:CPD-12843 CAS:82419-36-1 PMID:1804789 DrugBank:DB01165 PMID:3469159 PMID:35897550 Drug_Central:1981 PMID:9228220 PMID:11710934 PMID:3546152 PMID:36004580 LINCS:LSM-4370 PMID:15557076 HMDB:HMDB0015296 PMID:36228398 PMID:19646516 PMID:24550337 PMID:16669862 PMID:12827054 Reaxys:3657947 PMID:24497308 VSDB:1898 |
|
| definition |
A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. |
|
| formula |
C18H20FN3O4 |
|
| has part | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_59517 http://purl.obolibrary.org/obo/CHEBI_50750 |
|
| has_alternative_id |
CHEBI:100146 |
|
| has_exact_synonym |
rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
(+-)-ofloxacin racemic ofloxacin (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid ofloxacinum rac-ofloxacin rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid DL 8280 DL-8280 Exocin Floxin Gailuoxian HOE 280 HOE-280 OFLX ORF 18489 Ocuflox Oxaldin Prifloxcin Prifloxin Tarivid Visiren ofloxacin ofloxacine ofloxacino |
|
| has_RxCUI |
7623 |
|
| id |
CHEBI:7731 |
|
| in_subset | ||
| label |
Ofloxacin ofloxacin |
|
| mass |
361.373 |
|
| monoisotopicmass |
361.14378 |
|
| notation |
CHEBI:7731 |
|
| prefLabel |
Ofloxacin |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_87211 |