The Drug Ontology

Last uploaded: December 20, 2024
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Id http://purl.obolibrary.org/obo/CHEBI_7872
http://purl.obolibrary.org/obo/CHEBI_7872
Preferred Name

oxytocin
Definitions
A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour.
Synonyms
(1-Hemicystine)oxytocin
3-Isoleucine-8-leucine vasopressin
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
Endopituitrina
OT
OXT
Ocytocin
Orasthin
Pitocin
Piton S
Syntocinon
oxitocina
oxytocin
oxytocine
oxytocinum
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
Oxytocin
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Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour.
label
oxytocin
prefLabel
oxytocin
database_cross_reference
DrugBank:DB00107
PMID:19369205
HMDB:HMDB0002865
PMID:25209411
KEGG:D00089
PMID:10027619
PMID:19482229
PMID:10834934
PMID:19104313
PMID:18988842
PMID:15815422
PMID:10949083
PMID:33192340
PMID:18593851
Drug_Central:2042
KEGG:C00746
PMID:11134819
PMID:32683141
Wikipedia:Oxytocin
PMID:32979349
Patent:US3076797
CAS:50-56-6
PMID:24706799
PMID:10983343
PMID:13305558
Patent:US2938891
Beilstein:3586108
PMID:10949750
PMID:32509991
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notation
CHEBI:7872
in_subset
inchi
InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1
has_related_synonym
(1-Hemicystine)oxytocin
3-Isoleucine-8-leucine vasopressin
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
Endopituitrina
OT
OXT
Ocytocin
Orasthin
Pitocin
Piton S
Syntocinon
oxitocina
oxytocin
oxytocine
oxytocinum
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id
CHEBI:7872
charge
0
has_obo_namespace
chebi_ontology
formula
C43H66N12O12S2
subClassOf
inchikey
XNOPRXBHLZRZKH-DSZYJQQASA-N
mass
1007.18982
monoisotopicmass
1006.43646
type
smiles
[H][C@]1(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)[C@@H](C)CC
has_RxCUI
7824
has role
has_exact_synonym
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
Oxytocin
has characteristic
alternative label
(1-Hemicystine)oxytocin
3-Isoleucine-8-leucine vasopressin
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
Endopituitrina
OT
OXT
Ocytocin
Orasthin
Pitocin
Piton S
Syntocinon
oxitocina
oxytocin
oxytocine
oxytocinum
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
Oxytocin
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