Link to this page
The Drug Ontology
Last uploaded:
December 20, 2024
Jump to:
| Id | http://purl.obolibrary.org/obo/CHEBI_7862
http://purl.obolibrary.org/obo/CHEBI_7862
|
|---|---|
| Preferred Name | oxymetazoline |
| Definitions |
A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.
|
| Synonyms |
6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
oxymetazoline
oxymetazolina
oxymetazolinum
3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion. |
|---|---|
| label |
oxymetazoline
|
| prefLabel |
oxymetazoline
|
| database_cross_reference |
LINCS:LSM-2353
PMID:23679077
Drug_Central:2032
HMDB:HMDB0015070
PMID:4003266
CAS:1491-59-4
PMID:23988443
DrugBank:DB00935
Wikipedia:Oxymetazoline
KEGG:C07363
PMID:21177487
PMID:10487000
Patent:DE1117588
KEGG:D08322
Reaxys:886303
See more
See less
|
| notation |
CHEBI:7862
|
| in_subset | |
| inchi |
InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)
|
| has_related_synonym |
6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
oxymetazoline
oxymetazolina
oxymetazolinum
3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
See more
See less
|
| id |
CHEBI:7862
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| formula |
C16H24N2O
|
| subClassOf | |
| is conjugate base of | |
| inchikey |
WYWIFABBXFUGLM-UHFFFAOYSA-N
|
| mass |
260.37460
|
| monoisotopicmass |
260.18886
|
| type | |
| smiles |
Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C
|
| has_RxCUI |
7812
|
| has role | |
| has_exact_synonym |
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
|
| has characteristic | |
| alternative label |
6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
oxymetazoline
oxymetazolina
oxymetazolinum
3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
See more
See less
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |