The Drug Ontology

Last uploaded: December 20, 2024
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Id http://purl.obolibrary.org/obo/CHEBI_691037
http://purl.obolibrary.org/obo/CHEBI_691037
Preferred Name

desoximetasone
Definitions
Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis.
Synonyms
desoximetasona
desoximetasonum
desoximetasone
9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone
desoxymethasone
(11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis.
label
desoximetasone
prefLabel
desoximetasone
database_cross_reference
Patent:US3232839
Beilstein:2228097
Wikipedia:Desoximetasone
KEGG:D03697
Drug_Central:819
Patent:FR1296544
Patent:US3099654
CAS:382-67-2
DrugBank:DB00547
Patent:BE314196
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notation
CHEBI:691037
in_subset
inchi
InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
has_related_synonym
desoximetasona
desoximetasonum
desoximetasone
9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone
desoxymethasone
(11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
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id
CHEBI:691037
charge
0
has_obo_namespace
chebi_ontology
formula
C22H29FO4
subClassOf
inchikey
VWVSBHGCDBMOOT-IIEHVVJPSA-N
mass
376.46170
monoisotopicmass
376.20499
type
smiles
[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
has_RxCUI
3255
has role
has_exact_synonym
9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
has characteristic
alternative label
desoximetasona
desoximetasonum
desoximetasone
9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone
desoxymethasone
(11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
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