Link to this page
The Drug Ontology
Last uploaded:
December 20, 2024
Jump to:
| Id | http://purl.obolibrary.org/obo/CHEBI_6520
http://purl.obolibrary.org/obo/CHEBI_6520
|
|---|---|
| Preferred Name | lomustine |
| Definitions |
An N-nitrosourea that is urea in which one of the nitrogens is substituted by a 2-chloroethyl group and by a nitroso group, while the other nitrogen is substituted by a cyclohexyl group. An alkylating antineoplastic agent, it is used in the treatment of brain tumours, lung cancer, malignant melanoma and other solid tumours.
|
| Synonyms |
1-(2-chloroethyl)-3-cyclohexylnitrosourea
cyclohexyl chloroethyl nitrosourea
N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea
chloroethylcyclohexylnitrosourea
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
Belustine
CCNU
CINU
Cecenu
CeeNU
lomustina
lomustine
lomustinum
1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
See more
See less
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An N-nitrosourea that is urea in which one of the nitrogens is substituted by a 2-chloroethyl group and by a nitroso group, while the other nitrogen is substituted by a cyclohexyl group. An alkylating antineoplastic agent, it is used in the treatment of brain tumours, lung cancer, malignant melanoma and other solid tumours. |
|---|---|
| label |
lomustine
|
| prefLabel |
lomustine
|
| database_cross_reference |
PMID:24368412
PMID:19901016
Reaxys:2125058
PMID:22577051
KEGG:C07079
PMID:12153595
PMID:20719460
Drug_Central:1596
PMID:24293673
DrugBank:DB01206
CAS:13010-47-4
Wikipedia:Lomustine
HMDB:HMDB0015337
PMID:24516018
KEGG:D00363
PMID:6762924
See more
See less
|
| notation |
CHEBI:6520
|
| in_subset | |
| inchi |
InChI=1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
|
| has_related_synonym |
1-(2-chloroethyl)-3-cyclohexylnitrosourea
cyclohexyl chloroethyl nitrosourea
N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea
chloroethylcyclohexylnitrosourea
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
Belustine
CCNU
CINU
Cecenu
CeeNU
lomustina
lomustine
lomustinum
See more
See less
|
| id |
CHEBI:6520
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| formula |
C9H16ClN3O2
|
| subClassOf | |
| inchikey |
GQYIWUVLTXOXAJ-UHFFFAOYSA-N
|
| mass |
233.69500
|
| monoisotopicmass |
233.09310
|
| type | |
| smiles |
ClCCN(N=O)C(=O)NC1CCCCC1
|
| has_RxCUI |
6466
|
| has role | |
| has_exact_synonym |
1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
|
| has characteristic | |
| alternative label |
1-(2-chloroethyl)-3-cyclohexylnitrosourea
cyclohexyl chloroethyl nitrosourea
N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea
chloroethylcyclohexylnitrosourea
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
Belustine
CCNU
CINU
Cecenu
CeeNU
lomustina
lomustine
lomustinum
1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
See more
See less
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |