The Drug Ontology

Last uploaded: December 20, 2024
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Id http://purl.obolibrary.org/obo/CHEBI_64312
http://purl.obolibrary.org/obo/CHEBI_64312
Preferred Name

memantine
Definitions
A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
Synonyms
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
1-Amino-3,5-dimethyladamantane
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-aminoadamantane
1,3-Dimethyl-5-adamantanamine
memantina
memantine
memantinum
3,5-dimethyladamantan-1-amine
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
label
memantine
prefLabel
memantine
database_cross_reference
DrugBank:DB01043
Drug_Central:1679
PMID:22134197
PMID:21955815
KEGG:C13736
PMID:22300835
PMID:22030128
PMID:21953515
PMID:22329473
PMID:22414570
PMID:22245025
PMID:22392787
Wikipedia:Memantine
KEGG:D08174
PMID:22311362
Reaxys:2075983
PMID:22290557
PMID:20104942
Patent:US2011282100
PMID:22425751
LINCS:LSM-5154
CAS:19982-08-2
PMID:22327556
PMID:22297273
PMID:22248638
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notation
CHEBI:64312
in_subset
inchi
InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3
has_related_synonym
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
1-Amino-3,5-dimethyladamantane
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-aminoadamantane
1,3-Dimethyl-5-adamantanamine
memantina
memantine
memantinum
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id
CHEBI:64312
charge
0
has_obo_namespace
chebi_ontology
formula
C12H21N
has parent hydride
subClassOf
is conjugate base of
inchikey
BUGYDGFZZOZRHP-UHFFFAOYSA-N
mass
179.30180
monoisotopicmass
179.16740
has_alternative_id
CHEBI:34832
type
smiles
CC12CC3CC(C)(C1)CC(N)(C3)C2
has_RxCUI
6719
has role
has_exact_synonym
3,5-dimethyladamantan-1-amine
has characteristic
alternative label
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
1-Amino-3,5-dimethyladamantane
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-aminoadamantane
1,3-Dimethyl-5-adamantanamine
memantina
memantine
memantinum
3,5-dimethyladamantan-1-amine
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