The Drug Ontology

Last uploaded: December 20, 2024
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Id http://purl.obolibrary.org/obo/CHEBI_5801
http://purl.obolibrary.org/obo/CHEBI_5801
Preferred Name

hydroxychloroquine
Definitions
An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Synonyms
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline
oxichloroquine
7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
hydroxychloroquine
(+-)-hydroxychloroquine
Polirreumin
2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol
7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline
hidroxicloroquina
7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
hydroxychloroquinum
oxichlorochine
2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
NSC4375
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
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Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
label
hydroxychloroquine
prefLabel
hydroxychloroquine
database_cross_reference
DrugBank:DB01611
KEGG:C07043
HMDB:HMDB0015549
PMID:32295814
KEGG:D08050
PMID:23485647
PMID:32294807
PMCID:PMC7122276
PMID:32215614
PMID:23481418
PMID:23218706
PMID:32283236
CAS:118-42-3
PMID:32269046
Drug_Central:1395
Wikipedia:Hydroxychloroquine
PMID:32311324
Reaxys:253894
PMID:23216212
LINCS:LSM-5193
PMID:23902281
Patent:US2546658
PMID:23778483
PMID:23887202
PMID:32295788
PMID:23581274
PMID:32327429
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notation
CHEBI:5801
in_subset
inchi
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)
has_related_synonym
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline
oxichloroquine
7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
hydroxychloroquine
(+-)-hydroxychloroquine
Polirreumin
2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol
7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline
hidroxicloroquina
7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
hydroxychloroquinum
oxichlorochine
2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
NSC4375
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id
CHEBI:5801
charge
0
has_obo_namespace
chebi_ontology
formula
C18H26ClN3O
subClassOf
is conjugate base of
inchikey
XXSMGPRMXLTPCZ-UHFFFAOYSA-N
mass
335.87200
monoisotopicmass
335.17644
has functional parent
type
smiles
CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
has_RxCUI
5521
has role
has_exact_synonym
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
has characteristic
alternative label
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline
oxichloroquine
7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
hydroxychloroquine
(+-)-hydroxychloroquine
Polirreumin
2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol
7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline
hidroxicloroquina
7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
hydroxychloroquinum
oxichlorochine
2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
NSC4375
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
See more
See less
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