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The Drug Ontology
Last uploaded:
December 20, 2024
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| Id | http://purl.obolibrary.org/obo/CHEBI_4909
http://purl.obolibrary.org/obo/CHEBI_4909
|
|---|---|
| Preferred Name | etodolac |
| Definitions |
A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.
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| Synonyms |
1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
ETODOLIC ACID
(+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid
1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
etodolac
etodolaco
etodolacum
(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
ETODOLAC
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. |
|---|---|
| label |
etodolac
|
| prefLabel |
etodolac
|
| database_cross_reference |
Wikipedia:Etodolac
PMID:2970548
PMID:15369391
PMID:2527995
HMDB:HMDB0014887
Patent:DE2301525
LINCS:LSM-1781
DrugBank:DB00749
CAS:41340-25-4
PMID:28166217
Patent:US3939178
Drug_Central:1103
KEGG:D00315
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| notation |
CHEBI:4909
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| in_subset | |
| inchi |
InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)
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| has_related_synonym |
1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
ETODOLIC ACID
(+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid
1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
etodolac
etodolaco
etodolacum
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| id |
CHEBI:4909
|
| charge |
0
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| has_obo_namespace |
chebi_ontology
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| formula |
C17H21NO3
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| subClassOf | |
| inchikey |
NNYBQONXHNTVIJ-UHFFFAOYSA-N
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| mass |
287.35350
|
| monoisotopicmass |
287.15214
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| has_alternative_id |
CHEBI:126431
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| type | |
| smiles |
CCc1cccc2c3CCOC(CC)(CC(O)=O)c3[nH]c12
|
| has_RxCUI |
24605
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| has role | |
| has_exact_synonym |
(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
ETODOLAC
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| has characteristic | |
| alternative label |
1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
ETODOLIC ACID
(+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid
1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
etodolac
etodolaco
etodolacum
(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
ETODOLAC
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|
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