The Drug Ontology

Last uploaded: December 20, 2024

Id	http://purl.obolibrary.org/obo/CHEBI_44423 http://purl.obolibrary.org/obo/CHEBI_44423
Preferred Name	hydroxyurea
Definitions	A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.
Synonyms	carbamohydroxamic acid Hydroxycarbamide hidroxicarbamida Hydroxycarbamid carbamoyl oxime N-HYDROXYUREA hydroxycarbamidum N-carbamoylhydroxylamine carbamyl hydroxamate Hydroxyharnstoff carbamohydroximic acid hydroxycarbamide hydrea oxyurea Hydroxyurea hydroxyurea N-hydroxyurea See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.
label	hydroxyurea
prefLabel	hydroxyurea
database_cross_reference	KEGG:C07044 HMDB:HMDB0015140 Patent:US2705727 PMID:15772364 PMID:12107454 MetaCyc:HYDROXY-UREA Gmelin:130423 PMID:11365149 DrugBank:DB01005 CAS:127-07-1 KEGG:D00341 PMID:11391710 PMID:11285159 PMID:14988684 PMID:11364534 Wikipedia:Hydroxyurea PMID:15994344 PMID:23643402 Reaxys:1741548 Drug_Central:1399 Beilstein:1741548 PMID:22983419 PDBeChem:NHY PMID:23696560 PMID:23318979 PMID:9271088 PMID:11298103 PMID:16356682 See more See less
notation	CHEBI:44423
in_subset	http://purl.obolibrary.org/obo/chebi#3_STAR
inchi	InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
has_related_synonym	carbamohydroxamic acid Hydroxycarbamide hidroxicarbamida Hydroxycarbamid carbamoyl oxime N-HYDROXYUREA hydroxycarbamidum N-carbamoylhydroxylamine carbamyl hydroxamate Hydroxyharnstoff carbamohydroximic acid hydroxycarbamide hydrea oxyurea See more See less
id	CHEBI:44423
charge	0
has_obo_namespace	chebi_ontology
formula	CH4N2O2
subClassOf	http://purl.obolibrary.org/obo/CHEBI_64708 http://purl.obolibrary.org/obo/CHEBI_47857
inchikey	VSNHCAURESNICA-UHFFFAOYSA-N
mass	76.05474
monoisotopicmass	76.02728
has_alternative_id	CHEBI:44420 CHEBI:5816
type	http://www.w3.org/2002/07/owl#Class
smiles	NC(=O)NO
has_RxCUI	5552
has role	http://purl.obolibrary.org/obo/CHEBI_50905 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_50846 http://purl.obolibrary.org/obo/CHEBI_59517 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_50902 http://purl.obolibrary.org/obo/CHEBI_64911 http://purl.obolibrary.org/obo/CHEBI_74213 http://purl.obolibrary.org/obo/CHEBI_48578 See more See less
has_exact_synonym	Hydroxyurea hydroxyurea N-hydroxyurea
has characteristic	http://purl.obolibrary.org/obo/CHEBI_50905 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_50846 http://purl.obolibrary.org/obo/CHEBI_59517 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_50902 http://purl.obolibrary.org/obo/CHEBI_64911 http://purl.obolibrary.org/obo/CHEBI_74213 http://purl.obolibrary.org/obo/CHEBI_48578 See more See less
alternative label	carbamohydroxamic acid Hydroxycarbamide hidroxicarbamida Hydroxycarbamid carbamoyl oxime N-HYDROXYUREA hydroxycarbamidum N-carbamoylhydroxylamine carbamyl hydroxamate Hydroxyharnstoff carbamohydroximic acid hydroxycarbamide hydrea oxyurea Hydroxyurea hydroxyurea N-hydroxyurea See more See less

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