Link to this page
The Drug Ontology
Last uploaded:
December 20, 2024
Jump to:
| Id | http://purl.obolibrary.org/obo/CHEBI_38561
http://purl.obolibrary.org/obo/CHEBI_38561
|
|---|---|
| Preferred Name | fluvastatin |
| Definitions |
A racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia.
|
| Synonyms |
fluvastatina
(+-)-fluvastatin
(6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
fluvastatinum
rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid
fluvastatin
fluvastatine
rac-(3R,5S)-fluvastatin
erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid
Cranoc
rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
See more
See less
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia. |
|---|---|
| label |
fluvastatin
|
| prefLabel |
fluvastatin
|
| database_cross_reference |
KEGG:D07983
Patent:WO8402131
PMID:18452779
PMID:23846727
KEGG:C07014
PMID:18410471
CAS:93957-54-1
DrugBank:DB01095
Patent:US4739073
PMID:18936176
PMID:18413661
PMID:23212095
PMID:11273020
Wikipedia:Fluvastatin
Beilstein:9168031
PMID:12147804
See more
See less
|
| notation |
CHEBI:38561
|
| in_subset | |
| inchi |
InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m0/s1
|
| has_related_synonym |
fluvastatina
(+-)-fluvastatin
(6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
fluvastatinum
rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid
fluvastatin
fluvastatine
rac-(3R,5S)-fluvastatin
erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid
Cranoc
See more
See less
|
| id |
CHEBI:38561
|
| has part | |
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| formula |
C24H26FNO4
|
| subClassOf | |
| inchikey |
FJLGEFLZQAZZCD-JUFISIKESA-N
|
| mass |
411.467
|
| monoisotopicmass |
411.18459
|
| type | |
| smiles |
C1(=CC=C(C=C1)C=2C=3C(N(C2/C=C/[C@@H](C[C@@H](CC(O)=O)O)O)C(C)C)=CC=CC3)F
|
| has_RxCUI |
41127
|
| has role | |
| has_exact_synonym |
rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
|
| has characteristic | |
| alternative label |
fluvastatina
(+-)-fluvastatin
(6E)-erythro7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
fluvastatinum
rac-(3R,5S,6E)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid
fluvastatin
fluvastatine
rac-(3R,5S)-fluvastatin
erythro-(E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indol-2'-yl]hept-6-enoic acid
Cranoc
rac-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
See more
See less
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |