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The Drug Ontology
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December 20, 2024
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Id | http://purl.obolibrary.org/obo/CHEBI_28680
http://purl.obolibrary.org/obo/CHEBI_28680
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Preferred Name | cytarabine |
Definitions |
A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.
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Synonyms |
Cytosine-1-beta-D-arabinofuranoside
1-beta-D-Arabinofuranosylcytosine
Arabinoside C
cytosine-beta-D-arabinofuranoside
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
arabinocytosine
Cytosine arabinoside
cytarabinum
ara-C
citarabina
cytarabine
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
Cytarabine
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties. |
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label | cytarabine
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prefLabel | cytarabine
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database_cross_reference |
Wikipedia:Cytarabine
PMID:15492802
KEGG:C02961
LINCS:LSM-5470
CAS:147-94-4
Drug_Central:770
DrugBank:DB00987
HMDB:HMDB0015122
KEGG:D00168
Reaxys:89175
PDBeChem:AR3
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notation | CHEBI:28680
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in_subset | |
inchi | InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
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has_related_synonym |
Cytosine-1-beta-D-arabinofuranoside
1-beta-D-Arabinofuranosylcytosine
Arabinoside C
cytosine-beta-D-arabinofuranoside
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
arabinocytosine
Cytosine arabinoside
cytarabinum
ara-C
citarabina
cytarabine
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See less
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id | CHEBI:28680
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charge | 0
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has_obo_namespace | chebi_ontology
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formula | C9H13N3O5
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subClassOf | |
inchikey | UHDGCWIWMRVCDJ-CCXZUQQUSA-N
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mass | 243.21674
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monoisotopicmass | 243.08552
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has functional parent | |
has_alternative_id |
CHEBI:23532
CHEBI:40824
CHEBI:4074
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type | |
smiles | Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1
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has_RxCUI | 3041
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has role | |
has_exact_synonym |
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
Cytarabine
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has characteristic | |
alternative label |
Cytosine-1-beta-D-arabinofuranoside
1-beta-D-Arabinofuranosylcytosine
Arabinoside C
cytosine-beta-D-arabinofuranoside
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
arabinocytosine
Cytosine arabinoside
cytarabinum
ara-C
citarabina
cytarabine
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
Cytarabine
See more
See less
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