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The Drug Ontology
| Preferred Name | cytarabine | |
| Synonyms |
Cytosine-1-beta-D-arabinofuranoside 1-beta-D-Arabinofuranosylcytosine Arabinoside C cytosine-beta-D-arabinofuranoside 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone arabinocytosine Cytosine arabinoside cytarabinum ara-C citarabina cytarabine 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one Cytarabine |
|
| Definitions |
A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_28680 |
|
| alternative label |
Cytosine-1-beta-D-arabinofuranoside 1-beta-D-Arabinofuranosylcytosine Arabinoside C cytosine-beta-D-arabinofuranoside 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone arabinocytosine Cytosine arabinoside cytarabinum ara-C citarabina cytarabine 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one Cytarabine
|
|
| charge |
0
|
|
| database_cross_reference |
Wikipedia:Cytarabine PMID:15492802 KEGG:C02961 LINCS:LSM-5470 Beilstein:89175 CAS:147-94-4 Drug_Central:770 DrugBank:DB00987 HMDB:HMDB0015122 KEGG:D00168 Reaxys:89175 PDBeChem:AR3
|
|
| definition |
A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.
|
|
| formula |
C9H13N3O5
|
|
| has functional parent | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35705 http://purl.obolibrary.org/obo/CHEBI_35610 |
|
| has_alternative_id |
CHEBI:23532 CHEBI:40824 CHEBI:4074
|
|
| has_exact_synonym |
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one Cytarabine
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
Cytosine-1-beta-D-arabinofuranoside 1-beta-D-Arabinofuranosylcytosine Arabinoside C cytosine-beta-D-arabinofuranoside 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone arabinocytosine Cytosine arabinoside cytarabinum ara-C citarabina cytarabine
|
|
| has_RxCUI |
3041
|
|
| id |
CHEBI:28680
|
|
| in_subset | ||
| inchi |
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
|
|
| inchikey |
UHDGCWIWMRVCDJ-CCXZUQQUSA-N
|
|
| label |
cytarabine
|
|
| mass |
243.21674
|
|
| monoisotopicmass |
243.08552
|
|
| notation |
CHEBI:28680
|
|
| prefLabel |
cytarabine
|
|
| smiles |
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1
|
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_26440 |
| Delete | Subject | Author | Type | Created |
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