The Drug Ontology

Last uploaded: December 20, 2024
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Id http://purl.obolibrary.org/obo/CHEBI_28680
http://purl.obolibrary.org/obo/CHEBI_28680
Preferred Name

cytarabine
Definitions
A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.
Synonyms
Cytosine-1-beta-D-arabinofuranoside
1-beta-D-Arabinofuranosylcytosine
Arabinoside C
cytosine-beta-D-arabinofuranoside
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
arabinocytosine
Cytosine arabinoside
cytarabinum
ara-C
citarabina
cytarabine
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
Cytarabine
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Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.
label
cytarabine
prefLabel
cytarabine
database_cross_reference
Wikipedia:Cytarabine
PMID:15492802
KEGG:C02961
LINCS:LSM-5470
CAS:147-94-4
Drug_Central:770
DrugBank:DB00987
HMDB:HMDB0015122
KEGG:D00168
Reaxys:89175
PDBeChem:AR3
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notation
CHEBI:28680
in_subset
inchi
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
has_related_synonym
Cytosine-1-beta-D-arabinofuranoside
1-beta-D-Arabinofuranosylcytosine
Arabinoside C
cytosine-beta-D-arabinofuranoside
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
arabinocytosine
Cytosine arabinoside
cytarabinum
ara-C
citarabina
cytarabine
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id
CHEBI:28680
charge
0
has_obo_namespace
chebi_ontology
formula
C9H13N3O5
subClassOf
inchikey
UHDGCWIWMRVCDJ-CCXZUQQUSA-N
mass
243.21674
monoisotopicmass
243.08552
has functional parent
has_alternative_id
CHEBI:23532
CHEBI:40824
CHEBI:4074
type
smiles
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1
has_RxCUI
3041
has role
has_exact_synonym
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
Cytarabine
has characteristic
alternative label
Cytosine-1-beta-D-arabinofuranoside
1-beta-D-Arabinofuranosylcytosine
Arabinoside C
cytosine-beta-D-arabinofuranoside
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
arabinocytosine
Cytosine arabinoside
cytarabinum
ara-C
citarabina
cytarabine
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
Cytarabine
See more
See less
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