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Digital medicine Outcomes Value Set (DOVeS) Ontology
| Preferred Name | anaplastic astrocytoma | |
| Synonyms |
grade III astrocytic tumor anaplastic astrocytoma grade III astrocytoma malignant astrocytoma astrocytoma, anaplastic, malignant grade III astrocytic neoplasm |
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| Definitions |
Anaplastic astrocytoma is a rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0016684 |
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| altLabel |
grade III astrocytic tumor anaplastic astrocytoma grade III astrocytoma malignant astrocytoma astrocytoma, anaplastic, malignant grade III astrocytic neoplasm
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|
| definition |
Anaplastic astrocytoma is a rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord.
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| has_exact_synonym |
grade III astrocytic tumor anaplastic astrocytoma grade III astrocytoma malignant astrocytoma astrocytoma, anaplastic, malignant grade III astrocytic neoplasm
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| label |
anaplastic astrocytoma
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| prefixIRI |
MONDO:0016684
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| prefLabel |
anaplastic astrocytoma
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| textual definition |
Anaplastic astrocytoma is a rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord.
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| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0016680 |
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