Preferred Name |
severe combined immunodeficiency |
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Synonyms |
combined T and B cell inborn immunodeficiency severe combined immunodeficiency severe combined immunodeficiency (disease) SCID severe combined immunodeficiency disease |
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Definitions |
Severe combined immunodeficiency (SCID) comprises a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T lymphocytes resulting in early-onset severe respiratory infections and failure to thrive. They are classified according to immunological phenotype into SCID with absence of T cells but presence of B cells (T-B+ SCID) or SCID with absence of both (T-B- SCID). Both of these groups include several forms, with or without natural killer (NK) cells. |
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ID |
http://purl.obolibrary.org/obo/MONDO_0015974 |
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has_exact_synonym |
combined T and B cell inborn immunodeficiency severe combined immunodeficiency severe combined immunodeficiency (disease) SCID severe combined immunodeficiency disease |
|
IAO_0000589 |
severe combined immunodeficiency (disease) |
|
label |
severe combined immunodeficiency |
|
prefixIRI |
MONDO:0015974 |
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prefLabel |
severe combined immunodeficiency |
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textual definition |
Severe combined immunodeficiency (SCID) comprises a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T lymphocytes resulting in early-onset severe respiratory infections and failure to thrive. They are classified according to immunological phenotype into SCID with absence of T cells but presence of B cells (T-B+ SCID) or SCID with absence of both (T-B- SCID). Both of these groups include several forms, with or without natural killer (NK) cells. |
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disjointWith | ||
subClassOf |