loading...| Preferred Name | Cogan syndrome | |
| Synonyms |
Cogan syndrome Cogan's syndrome diffuse interstitual keratitis |
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| Definitions |
Cogan syndrome (CS) is a rare autoimmune disorder of unknown origin characterized by inflammatory ocular disease (mainly interstitial keratitis) and vestibulo-auditory manifestations (mainly acute onset hearing loss, tinnitus and vertigo), in the setting of a negative work-up for syphilis, with a variable risk of developing into a systemic disease. Systemic manifestations may occur in more than 70% of cases. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0015453 |
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| altLabel |
Cogan syndrome Cogan's syndrome diffuse interstitual keratitis |
|
| definition |
Cogan syndrome (CS) is a rare autoimmune disorder of unknown origin characterized by inflammatory ocular disease (mainly interstitial keratitis) and vestibulo-auditory manifestations (mainly acute onset hearing loss, tinnitus and vertigo), in the setting of a negative work-up for syphilis, with a variable risk of developing into a systemic disease. Systemic manifestations may occur in more than 70% of cases. |
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| has_exact_synonym |
Cogan syndrome Cogan's syndrome diffuse interstitual keratitis |
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| label |
Cogan syndrome |
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| prefixIRI |
MONDO:0015453 |
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| prefLabel |
Cogan syndrome |
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| textual definition |
Cogan syndrome (CS) is a rare autoimmune disorder of unknown origin characterized by inflammatory ocular disease (mainly interstitial keratitis) and vestibulo-auditory manifestations (mainly acute onset hearing loss, tinnitus and vertigo), in the setting of a negative work-up for syphilis, with a variable risk of developing into a systemic disease. Systemic manifestations may occur in more than 70% of cases. |
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| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0030703 http://purl.obolibrary.org/obo/MONDO_0000587 |