loading...| Preferred Name | granular cell tumor | |
| Synonyms |
neoplasm of granular cell granular cell tumor NOS (morphologic abnormality) GCT malignant variant of Abrikosov's tumor Abrikosoff's tumor Abrikosov’s tumor giant granulocellular Abrikosov's tumor Abrikosov's tumor Abrikosoff's granulous cell tumor granular cell tumor granular cell nerve sheath tumor granular cell myoblastoma granular cell schwannoma Abrikossoff's tumor granular cell neoplasm granular cell tumor (morphologic abnormality) Abrikossoff tumor |
|
| Definitions |
An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast. Editor note: MESH considers this a myoblastoma but we go with NCIT which states nerve sheath origin, consistent with GARD definition; also check ONCOTREE placement |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0006235 |
|
| comment |
Editor note: MESH considers this a myoblastoma but we go with NCIT which states nerve sheath origin, consistent with GARD definition; also check ONCOTREE placement |
|
| altLabel |
neoplasm of granular cell granular cell tumor NOS (morphologic abnormality) GCT malignant variant of Abrikosov's tumor Abrikosoff's tumor Abrikosov’s tumor giant granulocellular Abrikosov's tumor Abrikosov's tumor Abrikosoff's granulous cell tumor granular cell tumor granular cell nerve sheath tumor granular cell myoblastoma granular cell schwannoma Abrikossoff's tumor granular cell neoplasm granular cell tumor (morphologic abnormality) Abrikossoff tumor |
|
| definition |
An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast. Editor note: MESH considers this a myoblastoma but we go with NCIT which states nerve sheath origin, consistent with GARD definition; also check ONCOTREE placement |
|
| has_exact_synonym |
granular cell tumor granular cell nerve sheath tumor granular cell myoblastoma granular cell schwannoma Abrikossoff's tumor granular cell neoplasm granular cell tumor (morphologic abnormality) Abrikossoff tumor |
|
| has_narrow_synonym |
neoplasm of granular cell granular cell tumor NOS (morphologic abnormality) |
|
| has_related_synonym |
GCT malignant variant of Abrikosov's tumor Abrikosoff's tumor Abrikosov’s tumor giant granulocellular Abrikosov's tumor Abrikosov's tumor Abrikosoff's granulous cell tumor |
|
| label |
granular cell tumor |
|
| prefixIRI |
MONDO:0006235 |
|
| prefLabel |
granular cell tumor |
|
| seeAlso |
https://rarediseases.info.nih.gov/diseases/9618/granular-cell-tumor |
|
| textual definition |
An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast. |
|
| subClassOf |