Preferred Name | Leigh disease | |
Synonyms |
subacute necrotizing encephalomyelopathy juvenile subacute necrotizing encephalomyelopathy Infantile necrotizing encephalomyelopathy Leigh syndrome |
|
Definitions |
A cytochrome-c oxidase deficiency disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity. Xref MGI. OMIM mapping confirmed by DO. [SN]. |
|
ID |
http://purl.obolibrary.org/obo/DOID_3652 |
|
comment |
Xref MGI. OMIM mapping confirmed by DO. [SN]. |
|
database_cross_reference |
UMLS_CUI:C0023264 ICD10CM:G31.82 SNOMEDCT_US_2023_03_01:29570005 MESH:D007888 GARD:6877 MIM:256000 NCI:C84814 ORDO:506 |
|
definition |
A cytochrome-c oxidase deficiency disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity. |
|
has exact synonym |
juvenile subacute necrotizing encephalomyelopathy Infantile necrotizing encephalomyelopathy Leigh syndrome |
|
has symptom |
http://purl.obolibrary.org/obo/SYMP_0019145 http://purl.obolibrary.org/obo/SYMP_0000654 |
|
has_obo_namespace |
disease_ontology |
|
has_related_synonym |
subacute necrotizing encephalomyelopathy |
|
id |
DOID:3652 |
|
in_subset |
http://purl.obolibrary.org/obo/doid#NCIthesaurus |
|
label |
Leigh disease |
|
notation |
DOID:3652 |
|
prefLabel |
Leigh disease |
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subClassOf |