loading...| Preferred Name |
probucol |
|
| Synonyms |
Lurselle Biphenabid Bisbid DH-581 Serterol 4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol) probucolum 4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol) Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol C31H48O2S2 Lesterol Lorelco Superlipid Bisphenabid probucol |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_8427 |
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| AHFScode |
24:06.92 |
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| ATCCode |
C10AX02 |
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| CASRN |
23288-49-5 |
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| DBBrand |
lorelco bisphenabid sinlestal lesterol panavir lurselle lursell biphenabid bisbid |
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| DBname |
probucol |
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| DBSynonym |
4,4'- (isopropylidenedithio)bis(2, 6-di-tert-butylphenol) acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole 4,4'-(isopropylidenedithio)bis(2,6-di-tert-butylphenol) probucolum [inn-latin] acetone, bis (3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole 4,4'-(isopropylidenedithio)bis(2, 6-di-tert-butylphenol) 4,4'-(isopropylidenedithio)bis[2, 6-di-tert-butylphenol] acetone, bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole |
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| Definition |
A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood. |
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| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35679 http://purl.obolibrary.org/obo/CHEBI_22586 http://purl.obolibrary.org/obo/CHEBI_35821 |
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| InChI |
InChI=1S/C31H48O2S2/c1-27(2,3)21-15-19(16-22(25(21)32)28(4,5)6)34-31(13,14)35-20-17-23(29(7,8)9)26(33)24(18-20)30(10,11)12/h15-18,32-33H,1-14H3 |
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| InChIKey |
InChIKey=FYPMFJGVHOHGLL-UHFFFAOYSA-N |
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| inhibits | ||
| label |
probucol |
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| prefixIRI |
obo2:CHEBI_8427 |
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| prefLabel |
probucol |
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| related with | ||
| SMILES |
CC(C)(SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C CC(C)(Sc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)Sc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C |
|
| Synonym |
Lurselle Biphenabid Bisbid DH-581 Serterol 4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol) probucolum 4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol) Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol C31H48O2S2 Lesterol Lorelco Superlipid Bisphenabid probucol |
|
| xref |
CiteXplore:23378294 CASRN:23288-49-5 PharmGKB:PA451107 Wikipedia:Probucol PubChem Compound:4912 Reaxys:2026253 HMDB:HMDB15537 Drugs.com:http://www.drugs.com/cons/probucol.html Patent:US3862332 Drugs Product Database (DPD):2091909 Wikipedia:http://en.wikipedia.org/wiki/Probucol CiteXplore:23334712 KEGG DRUG:D00476 ChemSpider:4743 Patent:US3576883 KEGG COMPOUND:C07373 DrugBank:DB01599 CiteXplore:23741215 Patent:FR1561853 Patent:CN101423484 CiteXplore:23167559 CiteXplore:23363981 BindingDB:50007260 CiteXplore:23443157 CiteXplore:23107872 CiteXplore:22305809 PubChem Substance:46508876 Patent:CN101455842 Patent:CN102973535 ChEMBL:122641 |
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| subClassOf |