The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

lamotrigine

Synonyms

lamotrigina

Lamictal

lamotriginum

6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

C9H7Cl2N5

lamotrigine

3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine

ID

http://purl.obolibrary.org/obo/CHEBI_6367

AHFScode

28:12.92

ATCCode

N03AX09

CASRN

84057-84-1

DBBrand

lamictin

lamictal xr

lamictal cd

lamictal

DBname

lamotrigine

DBSynonym

gw 273293

lamotrigina [spanish]

lamotriginum [latin]

Definition

Lamotrigine is a member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6.

has effect

http://purl.obolibrary.org/obo/OAE_0000426

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0001425

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000573

http://purl.obolibrary.org/obo/OAE_0000411

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0000421

http://purl.obolibrary.org/obo/OAE_0000309

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000412

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0000207

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0001105

http://purl.obolibrary.org/obo/OAE_0001152

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000473

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000438

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001403

http://purl.obolibrary.org/obo/OAE_0000659

http://purl.obolibrary.org/obo/OAE_0000495

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000898

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001280

http://purl.obolibrary.org/obo/OAE_0001291

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000611

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000581

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000050

http://purl.obolibrary.org/obo/OAE_0000405

http://purl.obolibrary.org/obo/OAE_0000866

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000766

http://purl.obolibrary.org/obo/OAE_0001003

http://purl.obolibrary.org/obo/OAE_0000604

http://purl.obolibrary.org/obo/OAE_0001234

http://purl.obolibrary.org/obo/OAE_0001168

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000894

http://purl.obolibrary.org/obo/OAE_0001433

http://purl.obolibrary.org/obo/OAE_0000800

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000386

http://purl.obolibrary.org/obo/OAE_0001063

http://purl.obolibrary.org/obo/OAE_0000317

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0000479

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000286

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0000250

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0000586

http://purl.obolibrary.org/obo/OAE_0000967

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000482

http://purl.obolibrary.org/obo/OAE_0000424

http://purl.obolibrary.org/obo/OAE_0000597

http://purl.obolibrary.org/obo/OAE_0001170

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000330

http://purl.obolibrary.org/obo/OAE_0000469

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000447

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000691

http://purl.obolibrary.org/obo/OAE_0001369

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000275

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0001104

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0001360

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000612

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000995

http://purl.obolibrary.org/obo/OAE_0001336

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0001190

http://purl.obolibrary.org/obo/OAE_0000510

http://purl.obolibrary.org/obo/OAE_0001166

http://purl.obolibrary.org/obo/OAE_0000465

http://purl.obolibrary.org/obo/OAE_0001050

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000395

http://purl.obolibrary.org/obo/OAE_0000905

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000671

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000527

http://purl.obolibrary.org/obo/OAE_0000514

http://purl.obolibrary.org/obo/OAE_0001458

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0000825

http://purl.obolibrary.org/obo/OAE_0000526

http://purl.obolibrary.org/obo/OAE_0000882

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000433

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has role

http://purl.obolibrary.org/obo/CHEBI_35623

http://purl.obolibrary.org/obo/CHEBI_38215

http://purl.obolibrary.org/obo/CHEBI_60798

http://purl.obolibrary.org/obo/CHEBI_35469

http://purl.obolibrary.org/obo/CHEBI_35481

http://purl.obolibrary.org/obo/CHEBI_35477

InChI

InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)

InChIKey

InChIKey=PYZRQGJRPPTADH-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_3123

is metabolised by

http://purl.obolibrary.org/obo/dinto_1892

http://purl.obolibrary.org/obo/dinto_0270

is transported by

http://purl.obolibrary.org/obo/dinto_1440

label

lamotrigine

may interact with

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/dinto_DB00237

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/CHEBI_39867

http://purl.obolibrary.org/obo/CHEBI_7627

http://purl.obolibrary.org/obo/CHEBI_102166

http://purl.obolibrary.org/obo/CHEBI_4453

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB05246

http://purl.obolibrary.org/obo/CHEBI_68584

http://purl.obolibrary.org/obo/dinto_DB00977

http://purl.obolibrary.org/obo/dinto_DB01357

http://purl.obolibrary.org/obo/CHEBI_3766

http://purl.obolibrary.org/obo/CHEBI_3387

http://purl.obolibrary.org/obo/CHEBI_102524

http://purl.obolibrary.org/obo/dinto_DB00532

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/CHEBI_4888

prefixIRI

obo2:CHEBI_6367

prefLabel

lamotrigine

SMILES

Nc1nnc(c(N)n1)-c1cccc(Cl)c1Cl

NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1

Synonym

lamotrigina

Lamictal

lamotriginum

6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

C9H7Cl2N5

lamotrigine

3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine

xref

PubChem Substance:46505408

CASRN:84057-84-1

ChEMBL:138727

PharmGKB:PA450164

KEGG DRUG:D00354

BindingDB:50031299

Reaxys:7589268

Drugs.com:http://www.drugs.com/cdi/lamotrigine.html

NIST Chemistry WebBook:84057-84-1

PubChem Compound:3878

CiteXplore:21242744

Wikipedia:http://en.wikipedia.org/wiki/Lamotrigine

National Drug Code Directory:0173-0633-02

ChemSpider:3741

IUPHAR:2622

Wikipedia:Lamotrigine

ChEBI:6367

Drugs Product Database (DPD):2248232

DrugBank:DB00555

RxList:http://www.rxlist.com/cgi/generic/lamotrigine.htm

Guide To Pharmacology:2622

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/LNC/LP17251-7 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060528 LOINC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38703 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38703 NCIT LOOM
http://scai.fraunhofer.de/MSOntology#Lamotrigine MSO LOOM
http://purl.bioontology.org/ontology/VANDF/4020896 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148390 NDFRT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000328241 PDQ LOOM
http://purl.bioontology.org/ontology/RXNORM/28439 RXNORM LOOM
http://purl.bioontology.org/ontology/CPT/80175 CPT LOOM
http://purl.bioontology.org/ontology/NDDF/003988 NDDF LOOM
http://purl.bioontology.org/ontology/UATC/N03AX09 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0064636 OCHV LOOM
http://www.drugbank.ca/drugs/DB00555 FTC LOOM
http://www.co-ode.org/ontologies/galen#Lamotrigine GALEN LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387562000 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906050879505783 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-61170 SNMI LOOM
http://purl.bioontology.org/ontology/MESH/D000077213 MESH LOOM
http://stirdf.jst.go.jp/id/200907015386390689 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14273 OCHV LOOM
http://purl.bioontology.org/ontology/RCD/dnf.. RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C047781 RH-MESH LOOM
http://www.case.edu/EpSO.owl#Lamotrigine EPSO LOOM
http://purl.obolibrary.org/obo/CHEBI_6367 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6367 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6367 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6367 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6367 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6367 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6367 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6367 DRON SAME_URI