The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

ibuprofen

Synonyms

Liptan

(4-isobutylphenyl)-alpha-methylacetic acid

Nurofen

Nobfen

Dolo-Dolgit

(+-)-p-isobutylhydratropic acid

(+-)-2-(p-isobutylphenyl)propionic acid

Roidenin

2-[4-(2-methylpropyl)phenyl]propanoic acid

Ibumetin

Medipren

Inabrin

alpha-(p-isobutylphenyl)propionic acid

Mynosedin

Motrin

Butylenin

Urem

alpha-(4-isobutylphenyl)propionic acid

Ibuprofen

2-(4-isobutylphenyl)propanoic acid

Apsifen

4-isobutylhydratropic acid

Rufen

Suspren

(+-)-ibuprofen

Dolgirid

Lebrufen

Tabalon

Pediaprofen

Brufort

Dolgin

Inoven

Haltran

Ibu-Attritin

Buburone

Advil

Seclodin

(RS)-ibuprofen

Nobgen

Ebufac

Brufen

Bluton

Adran

C13H18O2

Anco

Ibuprocin

Lamidon

Trendar

Amibufen

Nuprin

Ibutid

Dolgit

Epobron

Femadon

Anflagen

(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid

ID

http://purl.obolibrary.org/obo/CHEBI_5855

AHFScode

28:08.04.92

ATCCode

C01EB16

M01AE14

M02AA13

G02CC01

M01AE01

binds

http://purl.obolibrary.org/obo/dinto_0103

CASRN

15687-27-1

DBBrand

mypaid

ifen

kratalgin

profen

ibu-ratiopharm

fenbid

anflagen

neobrufen

betaprofen

galprofen

ibrofen and ibugan

lebrufen

ibu-tab

ibuprocin

artofen

artril 300

dolo-dolgit

ibu-vivimed

profin

junior strength motrin

ibu-tab 200

alivium

dolgirid

andran

ibumax

panafen

spidifen

adran

anadin joint pain

alges-x

suspren

ibuxin

ebufac

bluton

alaxan

ibuprohm

dolormin

cap-profen

dolo-spedifen

femadon

tabalon

ibuprin

ibum

seclodin

ibutid

burana

lidifen

calprofen

haltran

midol 200

ibustar

ibu-attritin

napacetin

anadin ibuprofen

amibufen

algofren

ibuprosyn

inabrin

dismenol

moment

inoven

trendar

naron ace

children's elixsure

dalsy

dolgit

aktren

nuprin

epobron

nobfelon

ibux

pedia-profen

brufen

doloraz

ibalgin

bonifen

ibugesic

roidenin

spedifen

codral

narfen

midol

arthrofen

novogent n

speedpain nano

liptan

dolofort

lamidon

nurofen

ibuflam

ibuprom

nureflex

norvectan

algoflex

anco

perifar

betagesic

rimafen

advil liqui-gels

i-profen

children's advil

nobgen

fenbid spansule

neoprofen

fenpaed

herron blue

adex

ibuleve

ibuhexal

children's ibuprofen

act-3

ibu

tefin

nobfen

medipren

ibumetin

junior strength ibuprofen

apo-ibuprofen

brufen retard

tab-profen

ibufen

solpaflex

ibuprox

apsifen-f

lotem

ibupain

medicol

rapidol

ibugel

pantrop

pediatric advil

orbifen

butylenin

rafen

actiprofen

urem

ibumidol

ratiodolor

unafen

rufen

caldolor

ipren

bugesic

buburone

buprovil

amersol

eve

pediaprofen

mynosedin

brufort

junior strength advil

dolocyl

ranfen

motrin

myprodol

salvarina

children's motrin

emuprofen

rebugen

ibu-slo

novoprofen

espidifen

apsifen

diverin

brufanic

upfen

advil

dorival

paxofen

finalflex

DBname

ibuprofen

DBSynonym

ibuprophen

para-isobutylhydratropic acid

p-isobutylhydratropic acid

Definition

A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group.

has effect

http://purl.obolibrary.org/obo/OAE_0000081

http://purl.obolibrary.org/obo/OAE_0001057

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0001425

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0001068

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0000979

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0000666

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0001001

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000438

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0000496

http://purl.obolibrary.org/obo/OAE_0001186

http://purl.obolibrary.org/obo/OAE_0000659

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000335

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000611

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000242

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0000789

http://purl.obolibrary.org/obo/OAE_0000866

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0001003

http://purl.obolibrary.org/obo/OAE_0000604

http://purl.obolibrary.org/obo/OAE_0001339

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0001234

http://purl.obolibrary.org/obo/OAE_0001168

http://purl.obolibrary.org/obo/OAE_0000988

http://purl.obolibrary.org/obo/OAE_0000895

http://purl.obolibrary.org/obo/OAE_0001030

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0001054

http://purl.obolibrary.org/obo/OAE_0000811

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000674

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000506

http://purl.obolibrary.org/obo/OAE_0000839

http://purl.obolibrary.org/obo/OAE_0001147

http://purl.obolibrary.org/obo/OAE_0001400

http://purl.obolibrary.org/obo/OAE_0000597

http://purl.obolibrary.org/obo/OAE_0001170

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000447

http://purl.obolibrary.org/obo/OAE_0001393

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0001497

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0001360

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001370

http://purl.obolibrary.org/obo/OAE_0000243

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0001190

http://purl.obolibrary.org/obo/OAE_0001166

http://purl.obolibrary.org/obo/OAE_0000454

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000917

http://purl.obolibrary.org/obo/OAE_0001055

http://purl.obolibrary.org/obo/OAE_0000514

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000618

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2116

http://purl.obolibrary.org/obo/dinto_0938

has role

http://purl.obolibrary.org/obo/CHEBI_35475

http://purl.obolibrary.org/obo/CHEBI_35493

http://purl.obolibrary.org/obo/CHEBI_50630

http://purl.obolibrary.org/obo/CHEBI_35481

http://purl.obolibrary.org/obo/CHEBI_50629

InChI

InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

InChIKey

InChIKey=HEFNNWSXXWATRW-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0300

http://purl.obolibrary.org/obo/dinto_2828

http://purl.obolibrary.org/obo/dinto_0341

http://purl.obolibrary.org/obo/dinto_2116

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_4301

http://purl.obolibrary.org/obo/dinto_0938

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_1975

is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_1892

http://purl.obolibrary.org/obo/dinto_0265

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0276

http://purl.obolibrary.org/obo/dinto_1850

http://purl.obolibrary.org/obo/dinto_1221

http://purl.obolibrary.org/obo/dinto_1890

is transported by

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1322

label

ibuprofen

may interact with

http://purl.obolibrary.org/obo/dinto_DB00519

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/dinto_DB04865

http://purl.obolibrary.org/obo/CHEBI_2379

http://purl.obolibrary.org/obo/CHEBI_70707

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_47426

http://purl.obolibrary.org/obo/CHEBI_3082

http://purl.obolibrary.org/obo/dinto_DB01381

http://purl.obolibrary.org/obo/CHEBI_4856

http://purl.obolibrary.org/obo/dinto_DB08814

http://purl.obolibrary.org/obo/CHEBI_63622

http://purl.obolibrary.org/obo/dinto_DB06210

http://purl.obolibrary.org/obo/CHEBI_59594

http://purl.obolibrary.org/obo/CHEBI_44185

http://purl.obolibrary.org/obo/CHEBI_4876

http://purl.obolibrary.org/obo/dinto_DB01359

http://purl.obolibrary.org/obo/CHEBI_3437

http://purl.obolibrary.org/obo/CHEBI_6904

http://purl.obolibrary.org/obo/CHEBI_8499

http://purl.obolibrary.org/obo/CHEBI_41774

http://purl.obolibrary.org/obo/dinto_DB01356

http://purl.obolibrary.org/obo/CHEBI_7444

http://purl.obolibrary.org/obo/CHEBI_68845

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_71223

http://purl.obolibrary.org/obo/CHEBI_15365

http://purl.obolibrary.org/obo/dinto_DB00214

http://purl.obolibrary.org/obo/CHEBI_6343

http://purl.obolibrary.org/obo/CHEBI_3127

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/CHEBI_2904

http://purl.obolibrary.org/obo/dinto_DB00440

http://purl.obolibrary.org/obo/dinto_DB01580

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/CHEBI_258351

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_27999

http://purl.obolibrary.org/obo/CHEBI_3213

http://purl.obolibrary.org/obo/dinto_DB06209

http://purl.obolibrary.org/obo/CHEBI_8214

http://purl.obolibrary.org/obo/CHEBI_50861

http://purl.obolibrary.org/obo/CHEBI_238698

http://purl.obolibrary.org/obo/CHEBI_2567

modulates

http://purl.obolibrary.org/obo/dinto_2099

http://purl.obolibrary.org/obo/dinto_1645

prefixIRI

obo2:CHEBI_5855

prefLabel

ibuprofen

related with

http://purl.obolibrary.org/obo/dinto_0217

http://purl.obolibrary.org/obo/dinto_2153

http://purl.obolibrary.org/obo/dinto_0938

http://purl.obolibrary.org/obo/dinto_0800

SMILES

CC(C)CC1=CC=C(C=C1)C(C)C(O)=O

CC(C)Cc1ccc(cc1)C(C)C(O)=O

Synonym

Liptan

(4-isobutylphenyl)-alpha-methylacetic acid

Nurofen

Nobfen

Dolo-Dolgit

(+-)-p-isobutylhydratropic acid

(+-)-2-(p-isobutylphenyl)propionic acid

Roidenin

2-[4-(2-methylpropyl)phenyl]propanoic acid

Ibumetin

Medipren

Inabrin

alpha-(p-isobutylphenyl)propionic acid

Mynosedin

Motrin

Butylenin

Urem

alpha-(4-isobutylphenyl)propionic acid

Ibuprofen

2-(4-isobutylphenyl)propanoic acid

Apsifen

4-isobutylhydratropic acid

Rufen

Suspren

(+-)-ibuprofen

Dolgirid

Lebrufen

Tabalon

Pediaprofen

Brufort

Dolgin

Inoven

Haltran

Ibu-Attritin

Buburone

Advil

Seclodin

(RS)-ibuprofen

Nobgen

Ebufac

Brufen

Bluton

Adran

C13H18O2

Anco

Ibuprocin

Lamidon

Trendar

Amibufen

Nuprin

Ibutid

Dolgit

Epobron

Femadon

Anflagen

(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid

xref

NIST Chemistry WebBook:15687-27-1

Guide To Pharmacology:2713

CiteXplore:12723739

ChEBI:5855

CiteXplore:18697608

KEGG DRUG:D00126

ChemSpider:3544

IUPHAR:2713

PubChem Compound:3672

DrugBank:DB01050

CiteXplore:11433218

Patent:GB971700

PubChem Substance:46507255

Patent:US6727286

CiteXplore:14562167

Drugs Product Database (DPD):636525

Drugs.com:http://www.drugs.com/ibuprofen.html

CASRN:15687-27-1

CASRN:2049713

Patent:US3228831

Wikipedia:Ibuprofen

Wikipedia:http://en.wikipedia.org/wiki/Ibuprofen

ChEMBL:111674

KEGG COMPOUND:C01588

National Drug Code Directory:0182-8688-89

Patent:US3385886

Reaxys:2049713

RxList:http://www.rxlist.com/cgi/generic/ibup.htm

PDB:IBP

PharmGKB:PA449957

CiteXplore:21368281

CiteXplore:15506544

Patent:US5215755

CiteXplore:18335846

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.jp/bio/4/id/200906004759097752 IOBC LOOM
http://www.semanticweb.org/席婷/ontologies/2019/3/untitled-ontology-62#Ibuprofen PCALION LOOM
http://purl.jp/bio/4/id/200906005183226949 IOBC LOOM
http://www.drugbank.ca/drugs/DB01050 FTC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C561 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C561 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007052 RH-MESH LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Ibuprofen ADO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146197 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907012240750528 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387207008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/UATC/M01AE01 ATC LOOM
http://purl.bioontology.org/ontology/UATC/C01EB16 ATC LOOM
http://purl.bioontology.org/ontology/CSP/2270-2077 CRISP LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 HUPSON LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 HUPSON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 TXPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_5855 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/SNMI/C-603C0 SNMI LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004262 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/M02AA13 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4017840 VANDF LOOM
http://stirdf.jst.go.jp/id/200907069737148009 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002377 NDDF LOOM
http://www.co-ode.org/ontologies/galen#Ibuprofen GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#6519 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP16165-0 LOINC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040475 PDQ LOOM
http://purl.bioontology.org/ontology/LNC/LA14347-1 LOINC LOOM
http://purl.bioontology.org/ontology/MESH/D007052 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0020740 OCHV LOOM
http://purl.bioontology.org/ontology/UATC/R02AX02 ATC LOOM
http://www.projecthalo.com/aura#Ibuprofen AURA LOOM
http://scdontology.h3abionet.org/ontology/SCDO_0000606 SCDO LOOM
http://purl.bioontology.org/ontology/UATC/G02CC01 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/5640 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.701.430 RH-MESH LOOM