The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	ibuprofen
Synonyms	Femadon Lebrufen Inoven Anflagen (RS)-ibuprofen Nobgen Ibu-Attritin (+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid Apsifen Bluton Brufen Dolgit Nobfen Dolo-Dolgit Butylenin Inabrin (+-)-ibuprofen Epobron Roidenin Ibumetin 2-[4-(2-methylpropyl)phenyl]propanoic acid Liptan Advil Adran alpha-(4-isobutylphenyl)propionic acid Nurofen Motrin Dolgirid C13H18O2 Ibuprocin Medipren (4-isobutylphenyl)-alpha-methylacetic acid (+-)-2-(p-isobutylphenyl)propionic acid Haltran (+-)-p-isobutylhydratropic acid 4-isobutylhydratropic acid Urem Seclodin Ebufac Tabalon Brufort alpha-(p-isobutylphenyl)propionic acid Pediaprofen Ibutid Mynosedin Suspren Lamidon Ibuprofen Trendar Nuprin Rufen Anco Amibufen Dolgin Buburone 2-(4-isobutylphenyl)propanoic acid
ID	http://purl.obolibrary.org/obo/CHEBI_5855
AHFScode	28:08.04.92
ATCCode	M01AE14 M01AE01 M02AA13 C01EB16 G02CC01
binds	http://purl.obolibrary.org/obo/dinto_0103
CASRN	15687-27-1
DBBrand	nuprin dolormin artril 300 caldolor ibumetin buprovil nurofen naron ace ibux burana diverin fenbid ibuprox apsifen children's advil perifar mypaid orbifen narfen ipren emuprofen anadin ibuprofen ibu-tab 200 nobgen pediaprofen medipren pedia-profen inoven ibufen ibugesic nobfen junior strength motrin herron blue speedpain nano dismenol ebufac rufen fenpaed cap-profen ibustar moment actiprofen adex alivium ibum ibu-ratiopharm lamidon ibutid buburone advil lotem lidifen paxofen apo-ibuprofen ibuprocin rebugen children's motrin liptan neoprofen ibu-attritin roidenin nureflex ibu-vivimed alaxan novogent n ifen tefin novoprofen junior strength advil medicol codral alges-x act-3 unafen butylenin myprodol lebrufen dolo-spedifen betagesic dolo-dolgit brufen ibuprosyn pantrop fenbid spansule ibalgin bugesic ibuleve ibu rapidol adran dalsy ratiodolor bluton ibu-tab apsifen-f artofen espidifen profin ibuhexal urem dolgirid ibumidol rafen brufanic tabalon eve dolocyl mynosedin ibuprohm aktren ibuprom anco kratalgin trendar andran rimafen advil liqui-gels arthrofen ibrofen and ibugan dolofort children's elixsure panafen dorival napacetin ibumax profen brufen retard norvectan ibugel algofren galprofen nobfelon ibuflam motrin ibuprin solpaflex spedifen ibupain haltran i-profen children's ibuprofen betaprofen calprofen ibu-slo epobron tab-profen junior strength ibuprofen bonifen neobrufen finalflex algoflex seclodin pediatric advil dolgit amersol anadin joint pain suspren ibuxin inabrin anflagen midol 200 doloraz upfen spidifen femadon ranfen midol brufort amibufen salvarina
DBname	ibuprofen
DBSynonym	p-isobutylhydratropic acid ibuprophen para-isobutylhydratropic acid
Definition	A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000988 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000839 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001360 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001393 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0001370 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0001339 http://purl.obolibrary.org/obo/OAE_0000979 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0001168 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000895 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0001003 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001190 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0001425 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000666 http://purl.obolibrary.org/obo/OAE_0000674 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000438 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000917 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0001400 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0001030 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000514 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000242 http://purl.obolibrary.org/obo/OAE_0000462 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0001170 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0001497 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0001054 http://purl.obolibrary.org/obo/OAE_0000811 http://purl.obolibrary.org/obo/OAE_0000506 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_2116
has role	http://purl.obolibrary.org/obo/CHEBI_35493 http://purl.obolibrary.org/obo/CHEBI_50629 http://purl.obolibrary.org/obo/CHEBI_35475 http://purl.obolibrary.org/obo/CHEBI_35481 http://purl.obolibrary.org/obo/CHEBI_50630
InChI	InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
InChIKey	InChIKey=HEFNNWSXXWATRW-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_1987 http://purl.obolibrary.org/obo/dinto_2828 http://purl.obolibrary.org/obo/dinto_0341 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_2116 http://purl.obolibrary.org/obo/dinto_0300
is metabolised by	http://purl.obolibrary.org/obo/dinto_1890 http://purl.obolibrary.org/obo/dinto_1892 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_1850 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0265 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0276
is transported by	http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_1322
label	ibuprofen
may interact with	http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/dinto_DB00519 http://purl.obolibrary.org/obo/CHEBI_3213 http://purl.obolibrary.org/obo/dinto_DB08814 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_3437 http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/CHEBI_4856 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_15365 http://purl.obolibrary.org/obo/CHEBI_63622 http://purl.obolibrary.org/obo/dinto_DB00214 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_3127 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_238698 http://purl.obolibrary.org/obo/CHEBI_3441 http://purl.obolibrary.org/obo/dinto_DB06209 http://purl.obolibrary.org/obo/CHEBI_59594 http://purl.obolibrary.org/obo/dinto_DB04865 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/CHEBI_2904 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/dinto_DB01359 http://purl.obolibrary.org/obo/CHEBI_6904 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_2379 http://purl.obolibrary.org/obo/CHEBI_3082 http://purl.obolibrary.org/obo/dinto_DB01580 http://purl.obolibrary.org/obo/CHEBI_70707 http://purl.obolibrary.org/obo/CHEBI_4876 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/CHEBI_71223 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/CHEBI_47426 http://purl.obolibrary.org/obo/CHEBI_68845 http://purl.obolibrary.org/obo/CHEBI_6343 http://purl.obolibrary.org/obo/CHEBI_27999 http://purl.obolibrary.org/obo/dinto_DB01381 http://purl.obolibrary.org/obo/dinto_DB06210 http://purl.obolibrary.org/obo/CHEBI_258351 http://purl.obolibrary.org/obo/CHEBI_2567
modulates	http://purl.obolibrary.org/obo/dinto_1645 http://purl.obolibrary.org/obo/dinto_2099
prefixIRI	obo2:CHEBI_5855
prefLabel	ibuprofen
related with	http://purl.obolibrary.org/obo/dinto_2153 http://purl.obolibrary.org/obo/dinto_0800 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0217
SMILES	CC(C)Cc1ccc(cc1)C(C)C(O)=O CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
Synonym	Femadon Lebrufen Inoven Anflagen (RS)-ibuprofen Nobgen Ibu-Attritin (+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid Apsifen Bluton Brufen Dolgit Nobfen Dolo-Dolgit Butylenin Inabrin (+-)-ibuprofen Epobron Roidenin Ibumetin 2-[4-(2-methylpropyl)phenyl]propanoic acid Liptan Advil Adran alpha-(4-isobutylphenyl)propionic acid Nurofen Motrin Dolgirid C13H18O2 Ibuprocin Medipren (4-isobutylphenyl)-alpha-methylacetic acid (+-)-2-(p-isobutylphenyl)propionic acid Haltran (+-)-p-isobutylhydratropic acid 4-isobutylhydratropic acid Urem Seclodin Ebufac Tabalon Brufort alpha-(p-isobutylphenyl)propionic acid Pediaprofen Ibutid Mynosedin Suspren Lamidon Ibuprofen Trendar Nuprin Rufen Anco Amibufen Dolgin Buburone 2-(4-isobutylphenyl)propanoic acid
xref	Drugs Product Database (DPD):636525 IUPHAR:2713 PubChem Compound:3672 NIST Chemistry WebBook:15687-27-1 CiteXplore:18335846 Patent:US5215755 CASRN:15687-27-1 PDB:IBP KEGG COMPOUND:C01588 CiteXplore:18697608 Wikipedia:http://en.wikipedia.org/wiki/Ibuprofen Patent:GB971700 ChEMBL:111674 CiteXplore:21368281 KEGG DRUG:D00126 CiteXplore:11433218 ChemSpider:3544 Reaxys:2049713 Patent:US3385886 PubChem Substance:46507255 Patent:US3228831 CiteXplore:12723739 RxList:http://www.rxlist.com/cgi/generic/ibup.htm CiteXplore:14562167 CiteXplore:15506544 National Drug Code Directory:0182-8688-89 DrugBank:DB01050 Patent:US6727286 CASRN:2049713 PharmGKB:PA449957 Wikipedia:Ibuprofen Guide To Pharmacology:2713 Drugs.com:http://www.drugs.com/ibuprofen.html ChEBI:5855
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_5855	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	HOIP	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	COVID-19	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	HUPSON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	TXPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	CIDO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5855	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	CHEBI	LOOM
http://purl.bioontology.org/ontology/LNC/LA14347-1	LOINC	LOOM
http://purl.bioontology.org/ontology/LNC/LP16165-0	LOINC	LOOM
http://purl.bioontology.org/ontology/ATC/G02CC01	ATC	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040475	PDQ	LOOM
http://purl.bioontology.org/ontology/VANDF/4017840	VANDF	LOOM
http://stirdf.jst.go.jp/id/200907069737148009	IOBC	LOOM
http://purl.bioontology.org/ontology/SNMI/C-603C0	SNMI	LOOM
http://purl.bioontology.org/ontology/NDDF/002377	NDDF	LOOM
http://purl.jp/bio/4/id/200906005183226949	IOBC	LOOM
http://purl.obolibrary.org/obo/MESH_D007052	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.701.430	RH-MESH	LOOM
http://purl.bioontology.org/ontology/MESH/D007052	MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007052	RH-MESH	LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00406	OCIMIDO	LOOM
http://purl.bioontology.org/ontology/CSP/2270-2077	CRISP	LOOM
http://www.projecthalo.com/aura#Ibuprofen	AURA	LOOM
http://www.co-ode.org/ontologies/galen#Ibuprofen	GALEN	LOOM
http://purl.bioontology.org/ontology/ATC/M02AA13	ATC	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	HUPSON	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	CIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5855	NIFSTD	LOOM
http://www.drugbank.ca/drugs/DB01050	FTC	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016558	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/RXNORM/5640	RXNORM	LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Ibuprofen	STMSO	LOOM
http://purl.bioontology.org/ontology/ATC/M01AE01	ATC	LOOM
http://purl.jp/bio/4/id/200906004759097752	IOBC	LOOM
http://purl.obolibrary.org/obo/OMIT_0008185	OMIT	LOOM
http://purl.bioontology.org/ontology/ATC/R02AX02	ATC	LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Ibuprofen	ADO	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004262	LOINC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387207008	SNOMEDCT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C561	NCIT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0020740	OCHV	LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00348	COID	LOOM
https://go.drugbank.com/drugs/DB01050	MDM	LOOM
http://stirdf.jst.go.jp/id/200907012240750528	IOBC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#6519	OCHV	LOOM
http://purl.obolibrary.org/obo/NCIT_C561	BERO	LOOM
http://purl.obolibrary.org/obo/NCIT_C561	SCDO	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146197	NDFRT	LOOM
http://purl.bioontology.org/ontology/ATC/C01EB16	ATC	LOOM