The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	cefazolin
Synonyms	Cephazolin Cephamezine CEZ cefazolina cefazolin (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefazolinum Cefamezin Cephazoline (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefazoline 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylic acid C14H14N8O4S3 Cephazolidin
ID	http://purl.obolibrary.org/obo/CHEBI_474053
AHFScode	08:12.06.04
altId	CHEBI:3482
ATCCode	J01DB04
CASRN	25953-19-9
DBBrand	ancef
DBname	cefazolin
DBSynonym	cez cephazolin cefazoline cefazolin sodium
Definition	A cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side groups.
has effect	http://purl.obolibrary.org/obo/OAE_0001333 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001707 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000811 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0001434 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000805 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001243 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0000373
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0081 http://purl.obolibrary.org/obo/dinto_3995 http://purl.obolibrary.org/obo/dinto_0360 http://purl.obolibrary.org/obo/dinto_1450 http://purl.obolibrary.org/obo/dinto_3095
has role	http://purl.obolibrary.org/obo/CHEBI_36047
InChI	InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1
InChIKey	InChIKey=MLYYVTUWGNIJIB-BXKDBHETSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_0081 http://purl.obolibrary.org/obo/dinto_3995 http://purl.obolibrary.org/obo/dinto_3545 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_0360 http://purl.obolibrary.org/obo/dinto_1450 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_3095
is metabolised by	http://purl.obolibrary.org/obo/dinto_2265
is transported by	http://purl.obolibrary.org/obo/dinto_0300 http://purl.obolibrary.org/obo/dinto_0520
label	cefazolin
may interact with	http://purl.obolibrary.org/obo/dinto_DB00798 http://purl.obolibrary.org/obo/CHEBI_2637 http://purl.obolibrary.org/obo/dinto_DB00955 http://purl.obolibrary.org/obo/dinto_DB00684 http://purl.obolibrary.org/obo/CHEBI_8426
prefixIRI	obo2:CHEBI_474053
prefLabel	cefazolin
related with	http://purl.obolibrary.org/obo/dinto_0217
SMILES	[H][C@]12SCC(CSC3=NN=C(C)S3)=C(N1C(=O)[C@H]2NC(=O)CN1C=NN=N1)C(O)=O [H][C@]12SCC(CSc3nnc(C)s3)=C(N1C(=O)[C@H]2NC(=O)Cn1cnnn1)C(O)=O
Synonym	Cephazolin Cephamezine CEZ cefazolina cefazolin (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefazolinum Cefamezin Cephazoline (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefazoline 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylic acid C14H14N8O4S3 Cephazolidin
xref	Patent:US3516997 CiteXplore:6176550 ChEBI:474053 Beilstein:4169371 Drugs.com:http://www.drugs.com/cdi/cefazolin.html DrugBank:25953-19-9 Reaxys:4169371 National Drug Code Directory:0074-4732-03 CiteXplore:2083978 PharmGKB:PA448839 DrugBank:DB01327 CiteXplore:12569987 RxList:http://www.rxlist.com/cgi/generic/cefsod.htm KEGG DRUG:D02299 KEGG COMPOUND:C06880 Drugs Product Database (DPD):2108119 Wikipedia:http://en.wikipedia.org/wiki/Cefazolin CASRN:25953-19-9
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create New Mapping

Mapping To	Ontology	Source
http://purl.jp/bio/4/id/200906094247549391	IOBC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0007546	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.160	RH-MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/2180	RXNORM	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2562	OCHV	LOOM
http://purl.bioontology.org/ontology/MESH/D002437	MESH	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28913	NCIT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28913	NCIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.160	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	PHIPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	PHIPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	GENEPIO	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	GENEPIO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	CCONT	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	CCONT	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	GENEPIO	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	GENEPIO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_474053	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_474053	EFO	SAME_URI
http://purl.bioontology.org/ontology/NDDF/004841	NDDF	LOOM
http://purl.bioontology.org/ontology/UATC/J01DB04	ATC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060480	LOINC	LOOM
http://purl.obolibrary.org/obo/ARO_0000058	ARO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387470007	SNOMEDCT	LOOM
http://www.co-ode.org/ontologies/galen#Cefazolin	GALEN	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002437	RH-MESH	LOOM
http://stirdf.jst.go.jp/id/200907057147714728	IOBC	LOOM
http://purl.bioontology.org/ontology/LNC/LP16066-0	LOINC	LOOM
http://www.drugbank.ca/drugs/DB01327	FTC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.160	RH-MESH	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147751	NDFRT	LOOM
http://purl.bioontology.org/ontology/VANDF/4019659	VANDF	LOOM