The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	meropenem
Synonyms	(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID Antibiotic SM 7338 (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid meropenemum Meropenem meropenem C17H25N3O5S meropenem anhydrous (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
ID	http://purl.obolibrary.org/obo/CHEBI_43968
AHFScode	08:12.07.08
ATCCode	J01DH02
CASRN	119478-56-7
DBBrand	meronem merrem i.v. merrem
DBname	meropenem
DBSynonym	antibiotic sm 7338 meropenemum [inn-latin] meropenem anhydrous
Definition	A carbapenemcarboxylic acid that has formula C17H25N3O5S.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0001059 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000599 http://purl.obolibrary.org/obo/OAE_0000497 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0001333 http://purl.obolibrary.org/obo/OAE_0001369 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001243 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000797 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0000488 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0001298 http://purl.obolibrary.org/obo/OAE_0000811
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2744
has role	http://purl.obolibrary.org/obo/CHEBI_33282 http://purl.obolibrary.org/obo/CHEBI_36047
InChI	InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1
InChIKey	InChIKey=DMJNNHOOLUXYBV-PQTSNVLCSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_2744
is metabolised by	http://purl.obolibrary.org/obo/dinto_2961
label	meropenem
prefixIRI	obo2:CHEBI_43968
prefLabel	meropenem
SMILES	[H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O [H][C@]1([C@@H](C)O)C(=O)N2C(C(O)=O)=C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)[C@H](C)[C@]12[H]
Synonym	(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID Antibiotic SM 7338 (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid meropenemum Meropenem meropenem C17H25N3O5S meropenem anhydrous (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
xref	Patent:US4943569 RxList:http://www.rxlist.com/cgi/generic2/meropen.htm National Drug Code Directory:0310-0325-20 PDB:MER Wikipedia:Meropenem Beilstein:6826115 Drugs.com:http://www.drugs.com/cdi/meropenem.html Patent:EP126587 CASRN:96036-03-2 PDBeChem:MER Drugs Product Database (DPD):2218496 ChEBI:43968 Wikipedia:http://en.wikipedia.org/wiki/Meropenem DrugBank:DB00760 PharmGKB:PA164764445 ChEMBL:126386
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_43968	DOID	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	PHIPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	FRMO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	HHEAR	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_43968	GENEPIO	SAME_URI
http://purl.obolibrary.org/obo/XCO_0000575	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	PHIPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	DOID	LOOM
http://purl.bioontology.org/ontology/MESH/D000077731	MESH	LOOM
http://stirdf.jst.go.jp/id/200907021670336414	IOBC	LOOM
https://go.drugbank.com/drugs/DB00760	MDM	LOOM
http://purl.bioontology.org/ontology/NDDF/005166	NDDF	LOOM
http://purl.bioontology.org/ontology/VANDF/4021008	VANDF	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148477	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-537B0	SNMI	LOOM
http://purl.bioontology.org/ontology/ATC/J01DH02	ATC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1160	NCIT	LOOM
http://purl.bioontology.org/ontology/LNC/LP17167-5	LOINC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0066005	OCHV	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008102	LOINC	LOOM
http://purl.bioontology.org/ontology/RCD/eb9..	RCD	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387540000	SNOMEDCT	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	HHEAR	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_43968	GENEPIO	LOOM
http://purl.jp/bio/4/id/200906090814577410	IOBC	LOOM
http://purl.obolibrary.org/obo/NCIT_C1160	BERO	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041899	PDQ	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14375	OCHV	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026084	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/RXNORM/29561	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C059500	RH-MESH	LOOM
http://purl.obolibrary.org/obo/ARO_0000073	ARO	LOOM
http://www.co-ode.org/ontologies/galen#Meropenem	GALEN	LOOM